Synthesis

Synthesis of 1, 3, 4-thiadiazoles from aldehyde hydrazones

K Okuma, K Nagakura, Y Nakajima, K Kubo…

Index: Okuma, Kentaro; Nagakura, Kazuko; Nakajima, Yasutaka; Kubo, Kento; Shioji, Kosei Synthesis, 2004 , # 12 p. 1929 - 1931

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Citation Number: 7

Abstract

However, there is no report on the synthesis of 1 from simple aldehyde hydrazones 2. It is well known that the reaction of sterically crowded ketone hydrazones with disulfur dichloride in the presence of bases afforded thiones in good yields. [7] Recently, we have reported the synthesis of 1,3,4-selenadiazolines by the reaction of ketone hydrazones with diselenium dibromide, suggesting that the intermediates were not only selenoketones but also diazoalkanes. [8] These ...