Tetrahedron Letters

A convenient, rapid, and general synthesis of α-oxo thiocyanates using clay supported ammonium thiocyanate

HM Meshram, PB Thakur, BM Babu, VM Bangade

Index: Meshram; Thakur, Pramod B.; Madhu Babu; Bangade, Vikas M. Tetrahedron Letters, 2012 , vol. 53, # 14 p. 1780 - 1785

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Citation Number: 13

Abstract

A very rapid, convenient, and general method for the synthesis of α-oxo thiocyanates has been described by using clay supported ammonium thiocyanate. The procedure avoids the use of additional catalyst, solvent, aqueous work-up and the yields are high. Moreover, the method is applicable for a variety of aryl, heteroaryl, alkyl α-halo carbonyls, β-keto tosylates, α-halo β-dicarbonyl, α-tosyl, β-dicarbonyl, alkyl halide, and alkyl tosylates.