Intermolecular copper-catalyzed carbon-hydrogen bond activation via carbene insertion

MM Díaz-Requejo, TR Belderraín…

Index: Diaz-Requejo, M. Mar; Belderrain, Tomas R.; Nicasio, M. Carmen; Trofimenko, Swiatoslaw; Perez, Pedro J. Journal of the American Chemical Society, 2002 , vol. 124, # 6 p. 896 - 897

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Citation Number: 105

Abstract

A series of catalysts of general formula TpXCu (TpX= homoscorpionate ligand) promote the insertion of: CHCO2Et (ethyl diazoacetate as the carbene source) into the CH bonds of cycloalkanes and cyclic ethers in moderate to high yield. A correlation between the steric hindrance of these catalysts and the yield of the transformation has been observed.