Organic letters

Utility of Neodymium Diiodide as a Reductant in Ketone Coupling Reactions

WJ Evans, PS Workman, NT Allen

Index: Evans, William J.; Workman, Penny S.; Allen, Nathan T. Organic Letters, 2003 , vol. 5, # 12 p. 2041 - 2042

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Citation Number: 22

Abstract

The existence of Nd(II), an even more reducing divalent lanthanide, as a soluble molecular species was recently established by Bochkarev et al. 10 It was uncertain if Nd(II), which has a Ln(III)/Ln(II) reduction potential vs NHE of −2.6 V compared to Sm (−1.55 V), Tm (−2.3 V), and Dy (−2.5 V), 9 would be viable as a synthetic reagent. We report here that NdI 2 can be used as a lanthanide reducing agent in organic synthesis. In addition to being more reducing, ...