Organic letters

N, N-Diarylammonium Pyrosulfate as a Highly Effective Reverse Micelle-Type Catalyst for Hydrolysis of Esters

Y Koshikari, A Sakakura, K Ishihara

Index: Koshikari, Yoshiki; Sakakura, Akira; Ishihara, Kazuaki Organic Letters, 2012 , vol. 14, # 12 p. 3194 - 3197

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Citation Number: 9

Abstract

Reverse micelle-type N, N-diarylammonium pyrosulfate (3–5 mol%) efficiently catalyzes the hydrolysis of esters (up to 100 mmol scale) under organic solvent-free conditions. The present method is successfully applied to the hydrolysis of various esters without the decomposition of the base-sensitive moieties and without any loss of optical purity for α- heterosubstituted carboxylic acids.