Myristicin
Myristicin structure
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Common Name | Myristicin | ||
|---|---|---|---|---|
| CAS Number | 607-91-0 | Molecular Weight | 192.211 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 276.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C11H12O3 | Melting Point | <-20ºC | |
| MSDS | Chinese USA | Flash Point | 89.8±16.0 °C | |
| Symbol |
GHS08 |
Signal Word | Warning | |
Use of MyristicinMyristicine act as a serotonin receptor antagonist, a weak monamine oxidase (MAO) inhibitor. Myristicine is the main component of nutmeg essential oil from Myristica fragrans Houtt. Myristicine abuse produce hallucinogenic effects, organ damage, deliriumand others[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-methoxy-6-prop-2-enyl-1,3-benzodioxole |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Myristicine act as a serotonin receptor antagonist, a weak monamine oxidase (MAO) inhibitor. Myristicine is the main component of nutmeg essential oil from Myristica fragrans Houtt. Myristicine abuse produce hallucinogenic effects, organ damage, deliriumand others[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 276.5±0.0 °C at 760 mmHg |
| Melting Point | <-20ºC |
| Molecular Formula | C11H12O3 |
| Molecular Weight | 192.211 |
| Flash Point | 89.8±16.0 °C |
| Exact Mass | 192.078644 |
| PSA | 27.69000 |
| LogP | 3.26 |
| Appearance of Characters | oil | clear, light yellow |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.540 |
| InChIKey | BNWJOHGLIBDBOB-UHFFFAOYSA-N |
| SMILES | C=CCc1cc(OC)c2c(c1)OCO2 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H361f-H412 |
| Precautionary Statements | P201-P273-P308 + P313 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn |
| Risk Phrases | R52/53 |
| Safety Phrases | S61 |
| RIDADR | UN 3082 9/PG 3 |
| WGK Germany | 1 |
| RTECS | CY2625000 |
| Hazard Class | 9.0 |
| HS Code | 2932999099 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 7 | |
|---|---|
| DownStream 10 | |
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| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Myristicin from nutmeg induces apoptosis via the mitochondrial pathway and down regulates genes of the DNA damage response pathways in human leukaemia K562 cells.
Chem. Biol. Interact. 218 , 1-9, (2014) Myristicin, an allylbenzene, is a major active component of various spices, such as nutmeg and cinnamon, plants from the Umbelliferae family or in some essential oils, such as oils of clove or marjora... |
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Toxicological actions of plant-derived and anthropogenic methylenedioxyphenyl-substituted chemicals in mammals and insects.
J. Toxicol. Environ. Health. B. Crit. Rev. 15(6) , 365-95, (2012) The methylenedioxyphenyl (MDP) substituent is a structural feature present in many plant chemicals that deter foraging by predatory insects and herbivores. With increasing use of herbal extracts in al... |
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GC/GC-MS analysis, isolation and identification of bioactive essential oil components from the Bhutanese medicinal plant, Pleurospermum amabile.
Nat. Prod. Commun. 8(9) , 1305-8, (2013) We have hydrodistilled the essential oil (EO) from the aerial parts of the Bhutanese medicinal plant, Pleurospermum amabile using a Clevenger apparatus and evaluated this EO by GC/GC-MS and NMR analys... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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Name: Antioxidant activity in mouse brain homogenate assessed as inhibition of FeSO4/ascorb...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5245141
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Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600
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Name: Cytotoxicity against mouse RAW264.7 cells assessed as effect on cell viability at 10 ...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL4338176
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Name: Antioxidant activity in mouse brain homogenate assessed as inhibition of FeSO4/ascorb...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5245140
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Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| myristicine |
| 4-methoxy-6-prop-2-en-1-yl-1,3-benzodioxole |
| 6-Allyl-4-methoxy-1,3-benzodioxole |
| MFCD00133549 |
| Myristicin |
| 4-Méthoxy-6-(2-propèn-1-yl)-1,3-benzodioxole |
| 3-methoxy-4,5-methylenedioxyallylbenzene |
| 1-allyl-4,5-methylenedioxy-3-methoxybenzene |
| EINECS 210-146-9 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the InChIKey of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole? |
| A: InChIKey of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole is BNWJOHGLIBDBOB-UHFFFAOYSA-N. |
| Q: What English synonyms does 4-methoxy-6-prop-2-enyl-1,3-benzodioxole have? |
| A: English synonyms of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole: myristicine, 4-methoxy-6-prop-2-en-1-yl-1,3-benzodioxole, 6-Allyl-4-methoxy-1,3-benzodioxole, MFCD00133549, Myristicin, 4-Méthoxy-6-(2-propèn-1-yl)-1,3-benzodioxole, 3-methoxy-4,5-methylenedioxyallylbenzene, 1-allyl-4,5-methylenedioxy-3-methoxybenzene, EINECS 210-146-9. |
| Q: What is the melting point of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole? |
| A: Melting point of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole is <-20ºC. |
| Q: What is the boiling point of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole? |
| A: Boiling point of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole is 276.5±0.0 °C at 760 mmHg. |
| Q: What is the molecular formula of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole? |
| A: Molecular formula of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole is C11H12O3. |
| Q: What is the safety information for 4-methoxy-6-prop-2-enyl-1,3-benzodioxole? |
| A: Safety information for 4-methoxy-6-prop-2-enyl-1,3-benzodioxole: S61. |
| Q: What is the polar surface area (PSA) of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole? |
| A: Polar surface area (PSA) of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole is 27.69000. |
| Q: What is the SMILES notation of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole? |
| A: SMILES notation of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole is C=CCc1cc(OC)c2c(c1)OCO2. |
| Q: What is the English name of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole? |
| A: The English name of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole is 4-methoxy-6-prop-2-enyl-1,3-benzodioxole. |
| Q: What is the CAS number of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole? |
| A: CAS number of 4-methoxy-6-prop-2-enyl-1,3-benzodioxole is 607-91-0. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| Dayang Chem (Hangzhou) Co., Ltd. |
| naturewill |
| Henan Tianfu Chemical Co., Ltd. |