(R)-(-)-Nipecotic acid

Modify Date: 2026-07-10 18:54:20

(R)-(-)-Nipecotic acid Structure
(R)-(-)-Nipecotic acid structure
Common Name (R)-(-)-Nipecotic acid
CAS Number 25137-00-2 Molecular Weight 129.157
Density 1.1±0.1 g/cm3 Boiling Point 265.8±33.0 °C at 760 mmHg
Molecular Formula C6H11NO2 Melting Point 251-255 °C
MSDS Chinese Flash Point 114.5±25.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name (R)-(-)-Nipecotic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 265.8±33.0 °C at 760 mmHg
Melting Point 251-255 °C
Molecular Formula C6H11NO2
Molecular Weight 129.157
Flash Point 114.5±25.4 °C
Exact Mass 129.078979
PSA 49.33000
LogP -0.04
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.479
InChIKey XJLSEXAGTJCILF-RXMQYKEDSA-N
SMILES O=C(O)C1CCCNC1

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933399090

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles29

More Articles
Protein prosthesis: β-peptides as reverse-turn surrogates.

Protein Sci. 22(3) , 274-9, (2013)

The introduction of non-natural modules could provide unprecedented control over folding/unfolding behavior, conformational stability, and biological function of proteins. Success requires the interro...

N-methyl phenylalanine-rich peptides as highly versatile blood-brain barrier shuttles.

J. Med. Chem. 53 , 2354-63, (2010)

Here we studied the capacity of N-MePhe-(N-MePhe)(3)-CONH(2), Cha-(N-MePhe)(3)-CONH(2), and 2Nal-(N-MePhe)(3)-CONH(2) to carry various drugs (cargos) in in vitro blood-brain barrier (BBB) models in or...

GABA uptake by purified avian Müller glia cells in culture.

Neurotox. Res. 12(2) , 145-53, (2007)

GABA is the main inhibitory aminoacid transmitter present in neurons and glial cells. Its uptake is carried out by specific high-affinity Na(+)/Cl (-) dependent transporters (GATs). It has been report...

 (R)-(-)-Nipecotic acidBioassay

View more

Name: Inhibition of GABA uptake at murine BGT-1 expressed in HEK293 cells
Source: ChEMBL
Target: Sodium- and chloride-dependent betaine transporter
External Id: CHEMBL2405424
Name: Inhibitory activity against rat GABA transporter-2 (rGAT2)
Source: ChEMBL
Target: Sodium- and chloride-dependent GABA transporter 2
External Id: CHEMBL809055
Name: Inhibition of GABA uptake at murine GAT-3 expressed in HEK293 cells
Source: ChEMBL
Target: Sodium- and chloride-dependent GABA transporter 3
External Id: CHEMBL2405423
Name: Inhibition of GABA uptake at murine GAT-2 expressed in HEK293 cells
Source: ChEMBL
Target: Sodium- and chloride-dependent GABA transporter 2
External Id: CHEMBL2405422
Name: H-bonding interaction between amino acid residue (Thr-89) of Sodium- and chloride-dep...
Source: ChEMBL
Target: Sodium- and chloride-dependent GABA transporter 1
External Id: CHEMBL831438
Name: In vitro inhibition of [3H]GABA uptake in rat Hippocampal slices.
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL781269
Name: Effect on neuronal GABA(1 uM) uptake was measured using neurons cultured from cerebra...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL743386
Name: Inhibition of [3H]GABA uptake at mouse GAT1 expressed in HEK cells
Source: ChEMBL
Target: Sodium- and chloride-dependent GABA transporter 1
External Id: CHEMBL940676
Name: H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-de...
Source: ChEMBL
Target: Sodium- and chloride-dependent GABA transporter 1
External Id: CHEMBL830011
Name: H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-de...
Source: ChEMBL
Target: Sodium- and chloride-dependent GABA transporter 1
External Id: CHEMBL830010
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 Synonyms

hexahydronicotinic acid
(R)-Piperidine-3-carboxylic acid
(±)-Nipecotic acid
D-Piperidine-3-carboxylic acid
(±)-Piperidine-3-carboxylic acid
Nipecotic acid
(3R)-3-Piperidinecarboxylic acid
Piperidine-3-carboxylic acid
(S)-nipecotic acid
3-Piperidinecarboxylic acid
MFCD00211280
(R)-(–)-3-Piperidinecarboxylic acid
(R)-(-)-Nipecotic Acid
UNII:1U1QTN40SY
(3R)-Piperidine-3-carboxylic acid
R-nipecotic acid
(±)-3-Piperidine carboxylic acid
(R)-(-)-3-Piperidinecarboxylic Acid
(R)-(-)-Nipecoticacid
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