Name | Simvastatin ammonium salt | CAS# | 139893-43-9 | |
---|---|---|---|---|
Price | ¥Inquiry/1g | Purity | 98.9% | |
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1 Day | Stock | In Stock |
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Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene. |
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