2,2'-Methylenebis[(4S)-4-tert-butyl-2-oxazoline]

Modify Date: 2026-07-01 04:10:54

2,2'-Methylenebis[(4S)-4-tert-butyl-2-oxazoline] structure	Common Name	2,2'-Methylenebis[(4S)-4-tert-butyl-2-oxazoline]
	CAS Number	132098-54-5	Molecular Weight	266.379
	Density	1.1±0.1 g/cm3	Boiling Point	328.8±25.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₆N₂O₂	Melting Point	51-53ºC(lit.)
	MSDS	USA	Flash Point	124.8±15.7 °C
	Symbol	GHS07	Signal Word	Warning

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	(4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.1±0.1 g/cm3
Boiling Point	328.8±25.0 °C at 760 mmHg
Melting Point	51-53ºC(lit.)
Molecular Formula	C₁₅H₂₆N₂O₂
Molecular Weight	266.379
Flash Point	124.8±15.7 °C
Exact Mass	266.199432
PSA	43.18000
LogP	1.65
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.528
InChIKey	WCCCBUXURHZPQL-GHMZBOCLSA-N
SMILES	CC(C)(C)C1COC(CC2=NC(C(C)(C)C)CO2)=N1
Storage condition	2-8°C

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

MSDS(Chinese)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26
RIDADR	NONH for all modes of transport
WGK Germany	3.0

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

(S)-tert-Leucinol

CAS#:112245-13-3

Diethyl propane...

CAS#:10344-69-1

~69%

2,2'-Methyleneb...

CAS#:132098-54-5

Learn More

Literature: Denmark, Scott E.; Nakajima, Noriyuki; Stiff, Cory M.; Nicaise, Olivier J.-C.; Kranz, Michael Advanced Synthesis and Catalysis, 2008 , vol. 350, # 7-8 p. 1023 - 1045

N1,N3-bis((S)-1...

CAS#:133463-95-3

~42%

2,2'-Methyleneb...

CAS#:132098-54-5

N/A

CAS#:133464-00-3

Learn More

Literature: Helvetica Chimica Acta, , vol. 74, # 1 p. 232 - 240

N/A

CAS#:133464-00-3

2,2'-Methyleneb...

CAS#:132098-54-5

Learn More

Literature: Helvetica Chimica Acta, , vol. 74, # 1 p. 232 - 240

(S)-tert-Leucinol

CAS#:112245-13-3

2,2'-Methyleneb...

CAS#:132098-54-5

Learn More

Literature: Helvetica Chimica Acta, , vol. 74, # 1 p. 232 - 240

N1,N3-bis((S)-1...

CAS#:133463-95-3

2,2'-Methyleneb...

CAS#:132098-54-5

Learn More

Literature: Helvetica Chimica Acta, , vol. 74, # 1 p. 232 - 240

malonodiimidic ...

CAS#:878766-81-5

(S)-tert-Leucinol

CAS#:112245-13-3

2,2'-Methyleneb...

CAS#:132098-54-5

Learn More

Literature: Chemistry - An Asian Journal, , vol. 6, # 1 p. 78 - 82

(S)-tert-Leucinol

CAS#:112245-13-3

Diethyl malonate

CAS#:105-53-3

2,2'-Methyleneb...

CAS#:132098-54-5

Learn More

Literature: Tetrahedron Letters, , vol. 31, # 42 p. 6005 - 6008

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 4
CAS#:112245-13-3 (S)-tert-Leucinol CAS#:10344-69-1 Diethyl propane... CAS#:878766-81-5 malonodiimidic ... CAS#:105-53-3 Diethyl malonate
DownStream 1
CAS#:131833-93-7 (S,S)-(-)-2,2'-...

This table lists relevant public references with title, journal and publication metadata for this compound.

Gant, T.G. Meyers, A.I.

Tetrahedron 50 , 2297, (1994)

Pfaltz, A.

Acc. Chem. Res. 26 , 339, (1993)

Bolm, C.

Angew. Chem. Int. Ed. Engl. 30 , 542, (1991)

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262

Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA

Name: Screen for inhibitors of RMI FANCM (MM2) intereaction
Source: 11908
Target: N/A
External Id: RMI-FANCM-MM2

Name: Inhibitors of CDC25B-CDK2/CyclinA interaction
Source: Center for Chemical Genomics, University of Michigan
External Id: MScreen:TargetID_600

Name: High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS1303

Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979

Name: A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Chain A, Poliovirus Polymerase With Gtp
External Id: HMS750

Total 7, Current Page 1 of 1

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

MFCD00192290

(S,S)-2,2'-Methylenebis(4-tert-butyl-2-oxazoline)

2,2'-Methylenebis[(4S)-4-tert-butyl-2-oxazoline]

(4S,4'S)-2,2'-Methylenebis[4-(2-methyl-2-propanyl)-4,5-dihydro-1,3-oxazole]

tBuBOX

hms1526d16

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the molecular weight of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole?

A: Molecular weight of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole is 266.379.

Q: What is the LogP of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole?

A: LogP of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole is 1.65.

Q: What are the upstream materials of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole?

A: Related upstream materials(CAS) of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole: 112245-13-3;10344-69-1;878766-81-5;105-53-3.

Q: What are the storage conditions for (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole?

A: Storage conditions for (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole: 2-8°C.

Q: What is the boiling point of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole?

A: Boiling point of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole is 328.8±25.0 °C at 760 mmHg.

Q: What are the downstream products of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole?

A: Related downstream products(CAS) of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole: 131833-93-7.

Q: What is the CAS number of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole?

A: CAS number of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole is 132098-54-5.

Q: What is the melting point of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole?

A: Melting point of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole is 51-53ºC(lit.).

Q: What is the SMILES notation of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole?

A: SMILES notation of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole is CC(C)(C)C1COC(CC2=NC(C(C)(C)C)CO2)=N1.

Q: What English synonyms does (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole have?

A: English synonyms of (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole: MFCD00192290, (S,S)-2,2'-Methylenebis(4-tert-butyl-2-oxazoline), 2,2'-Methylenebis[(4S)-4-tert-butyl-2-oxazoline], (4S,4'S)-2,2'-Methylenebis[4-(2-methyl-2-propanyl)-4,5-dihydro-1,3-oxazole], tBuBOX, hms1526d16.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

2,2'-Methylenebis[(4S)-4-tert-butyl-2-oxazoline]

Names

Chemical & Physical Properties

MSDS

Safety Information

Synthetic Route

Precursor & DownStream

Articles3

Bioassay

Synonyms

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.