(Z)-GW 5074

Modify Date: 2024-01-10 10:27:06

(Z)-GW 5074 structure	Common Name	(Z)-GW 5074
	CAS Number	1233748-60-1	Molecular Weight	520.94
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₈Br₂INO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (Z)-GW 5074

(Z)-GW 5074 is a compound which interacts with both mHTT (mutant huntingtin protein) and LC3, but not but not with the wild-type HTT protein. (Z)-GW 5074 inhibits c-Raf, shows no effect on autophagy, and is effective for neurodegenerative disorder[1].

Name	(Z)-GW 5074

Description	(Z)-GW 5074 is a compound which interacts with both mHTT (mutant huntingtin protein) and LC3, but not but not with the wild-type HTT protein. (Z)-GW 5074 inhibits c-Raf, shows no effect on autophagy, and is effective for neurodegenerative disorder[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> Raf
Target	c-Raf
References	[1]. Li Z, et al. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds. Nature. 2019 Oct 30.

Molecular Formula	C₁₅H₈Br₂INO₂
Molecular Weight	520.94

(Z)-GW 5074

Use of (Z)-GW 5074

Names

(Z)-GW 5074 Biological Activity

Chemical & Physical Properties