(Z)-GW 5074

Modify Date: 2024-01-10 10:27:06

(Z)-GW 5074 Structure
(Z)-GW 5074 structure
Common Name (Z)-GW 5074
CAS Number 1233748-60-1 Molecular Weight 520.94
Density N/A Boiling Point N/A
Molecular Formula C15H8Br2INO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (Z)-GW 5074


(Z)-GW 5074 is a compound which interacts with both mHTT (mutant huntingtin protein) and LC3, but not but not with the wild-type HTT protein. (Z)-GW 5074 inhibits c-Raf, shows no effect on autophagy, and is effective for neurodegenerative disorder[1].

 Names

Name (Z)-GW 5074

 (Z)-GW 5074 Biological Activity

Description (Z)-GW 5074 is a compound which interacts with both mHTT (mutant huntingtin protein) and LC3, but not but not with the wild-type HTT protein. (Z)-GW 5074 inhibits c-Raf, shows no effect on autophagy, and is effective for neurodegenerative disorder[1].
Related Catalog
Target

c-Raf

References

[1]. Li Z, et al. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds. Nature. 2019 Oct 30.

 Chemical & Physical Properties

Molecular Formula C15H8Br2INO2
Molecular Weight 520.94
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