HER2-IN-13
Modify Date: 2024-01-10 18:40:38
HER2-IN-13 structure
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Common Name | HER2-IN-13 | ||
|---|---|---|---|---|
| CAS Number | 2414056-34-9 | Molecular Weight | 568.96 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H23ClF2N8O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HER2-IN-13HER2-IN-13 (Compound 33) is an HER2 inhibitor with an IC50 of 8 nM. HER2-IN-13 also inhibits wt-EGFR with an IC50 of 0.40 μM[1]. |
| Name | HER2-IN-13 |
|---|
| Description | HER2-IN-13 (Compound 33) is an HER2 inhibitor with an IC50 of 8 nM. HER2-IN-13 also inhibits wt-EGFR with an IC50 of 0.40 μM[1]. |
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| Related Catalog | |
| Target |
HER2:8 nM (IC50) EGFR (WT):0.40 μM (IC50) hERG:13.3 μM (IC50) |
| In Vitro | HER2-IN-13 (Compound 33) 抑制 hERG 通道，IC50 为 13.3 μM[1]。 |
| References |
[1]. Ding Zhou, et al. Quinazoline derivatives as antitumor agents. Patent WO2020057511A1. |
| Molecular Formula | C26H23ClF2N8O3 |
|---|---|
| Molecular Weight | 568.96 |