Ananas comosus

Names

[ Name ]:
Ananas comosus

[Synonym ]:
EINECS 253-387-5
MFCD00081423

Biological Activity

[Description]:

Stem bromelain (EC 3.4.22.32) is a cysteine proteinase, isolated from pineapple (Ananas comosus) stem. Stem bromelain is a major bromelain, which exhibits various fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory activities. Stem bromelain has in vivo antitumoral and antileukemic activity, as well as antimetastatic action[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

[References]

[1]. Pavan R, et al. Properties and therapeutic application of bromelain: a review. Biotechnol Res Int. 2012;2012:976203.

[2]. Báez R, et al. In vivo antitumoral activity of stem pineapple (Ananas comosus) bromelain. Planta Med. 2007 Oct;73(13):1377-83.

Chemical & Physical Properties

[ Molecular Formula ]:
n_.a_.

[ Appearance of Characters ]:
powder | yellow-brown

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: soluble1.0mg/mL, clear, colorless

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H319-H334-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338-P342 + P311

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
36/37/38-42

[ Safety Phrases ]:
22-24-26-36/37-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ HS Code ]:
35079090

Articles

Inhibitory effects of bromelain, a cysteine protease derived from pineapple stem (Ananas comosus), on intestinal motility in mice.

Neurogastroenterol. Motil. 23(8) , 745-e331, (2011)

Bromelain (BR) is a cysteine protease with inhibitory effects on intestinal secretion and inflammation. However, its effects on intestinal motility are largely unexplored. Thus, we investigated the ef...

Trifluoroethanol stabilizes the molten globule state and induces non-amyloidic turbidity in stem bromelain near its isoelectric point.

Int. J. Biol. Macromol. 49 , 536-542, (2011)

Stem bromelain (SBM) is a therapeutic protein that has been studied for alkaline denaturation in the intestines, the principal site of its absorption. In this study, we investigated fluorinated alcoho...

Concentration-dependent antagonistic persuasion of SDS and naphthalene derivatives on the fibrillation of stem bromelain.

Arch. Biochem. Biophys. 540(1-2) , 101-16, (2013)

Sodium dodecyl sulfate, a biological membrane mimetic, can be used to study the conversion of globular proteins into amyloid fibrils in vitro. Using multiple approaches, the effect of SDS was examined...

Related Compounds

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