L-(+)-Arabinose

Names

[ Name ]:
L-(+)-Arabinose

[Synonym ]:
L-(+)-Arabinose
(+)-Arabinose
EINECS 226-214-6
Arabinose
L-arabino-pentose
MFCD00135866
L-Arabinose

Biological Activity

[Description]:

L-(+)-Arabinose selectively inhibits intestinal sucrase activity in a noncompetitive manner and suppresses the plasma glucose increase due to sucrose ingestion.

[Related Catalog]:

Natural Products >> Saccharides and Glycosides

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[In Vitro]

L-(+)-Arabinose selectively inhibits intestinal sucrase activity in a noncompetitive manner and suppresses the plasma glucose increase due to sucrose ingestion[1]. L-(+)-Arabinose is found to be associated with ribose-5-phosphate isomerase deficiency, which is an inborn error of metabolism[2].

[References]

[1]. Osaki S, et al. L-arabinose feeding prevents increases due to dietary sucrose in lipogenic enzymes and triacylglycerol levels in rats. J Nutr. 2001 Mar;131(3):796-9.

[2]. Huck JH, et al. Ribose-5-phosphate isomerase deficiency: new inborn error in the pentose phosphate pathway associated with a slowly progressive leukoencephalopathy. Am J Hum Genet. 2004 Apr;74(4):745-51.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
415.5±38.0 °C at 760 mmHg

[ Melting Point ]:
155ºC

[ Molecular Formula ]:
C₅H₁₀O₅

[ Molecular Weight ]:
150.130

[ Flash Point ]:
219.2±23.3 °C

[ Exact Mass ]:
150.052826

[ PSA ]:
97.99000

[ LogP ]:
-2.39

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.544

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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Related Compounds

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