1337529-56-2

• 常用中文名：N-[(R)-(2,3,4,5,6-五氟苯氧基)苯氧基亚膦酰基]-L-丙氨酸异丙酯
• 常用英文名：(S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester
• CAS号：1337529-56-2
• 分子式：C₁₈H₁₇F₅NO₅P
• 分子量：453.29700
• 相关类别： 研究领域 感染
• 发布时间：2016-04-17 09:52:07
• 更新时间：2026-08-03 11:55:05
• 异丙基((R)-(全氟苯氧基)(苯氧基)磷酰基)-L-丙氨酸盐可用于合成索非布韦(HY-15005),以避免产生索非布威降解杂质[1]。

名称

• 中文名: N-[(R)-(2,3,4,5,6-五氟苯氧基)苯氧基亚膦酰基]-L-丙氨酸异丙酯
• 英文名: (S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester
• 中文别名: ((R)-(全氟苯氧基)(苯氧基)磷酰基)-L-丙氨酸异丙基酯; 索菲布韦杂质57; 380#异构; 索磷布韦杂质11; 索福斯布韦杂质1; 索氟布韦杂质14; 索福斯布韦杂质U
• 英文别名: 380#Heterogeneous; .2(S)-[((R)-2,3,4,5,6-pentafluoro-phenoxy)-phenoxy-phosphorylamino]propionic acid isopropyl ester; propan-2-yl (2S)-2-{[(R)-(2,3,4,5,6-pentafluorophenoxy)(phenoxy)phosphoryl]amino}propanoate; .(S)-isopropyl-2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate; .(S)-isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate; propan-2-yl (2S)-2-[[(R)-pentafluorophenoxy(phenoxy)phosphoryl]amino]propanoate; Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate; N-[(R)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-methylethyl ester; L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester; isopropyl (2S)-2-[[(R)-(2,3,4,5,6-pentafluorophenoxy)-phenoxy-phosphoryl]amino]propanoate; .(S)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate; (S)-isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate; N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine-1-methylethyl esterQ: What is N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine-1-methylethyl ester Q: What is the CAS Number of N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine-1-methylethyl ester

物化性质

• 分子式: C₁₈H₁₇F₅NO₅P
• 分子量: 453.29700
• 精确质量: 453.07600
• PSA: 83.67000
• LogP: 5.26860
• 储存条件: 室温

生物活性

• 描述: 异丙基((R)-(全氟苯氧基)(苯氧基)磷酰基)-L-丙氨酸盐可用于合成索非布韦(HY-15005),以避免产生索非布威降解杂质[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Shi GH, et al. The preparation of Suo Feibuwei. CN109535213A.