Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFU-CHEM - Citral
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Citral
Price: ￥Inquiry/25kg
Purity: 99.0%
Stocking Period: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

5392-40-5

5392-40-5 structure

Name: Citral
Chemical Name: citral
CAS Number: 5392-40-5
Molecular Formula: C₁₀H₁₆O
Molecular Weight: 152.233
Catalog: Flavors and spices Synthetic spice Aldehyde Nonenal
Create Date: 2018-02-05 08:00:00
Modify Date: 2026-07-01 18:36:36
Citral is a monoterpene found in Cymbopogon citratus essential oil, with antihyperalgesic, anti-nociceptive and anti-inflammatory effects[1].

Name	citral
Synonyms	Citralcistrans 3,7-Dimethyl-2,6-octadienal,Geranial and neral mixture CITRAL 95 2,6-Octadienal, 3,7-dimethyl citral,mixtureofcisandtrans 3,7-DIMETHYL-2,6-OCTADIENALDEHYDE NERAL CITRAL CITRAL NATURAL LEMOME 6-Octadienal,3,7-dimethyl-2 LEMSYN GERANIAL 3,7-DIMETHYL-2,6-OCTADIENAL 3,7-dimethyl-trans-2,6-octadienal 3,7-dimethyl-octa-2,6-dienal CIS/TRANS-3,7-DIMETHYL-2,6-OCTADIEN-1-AL Z-3,7-Dimethyl-2,6-octadiene-1-al CITRAL MIXTURE OF CIS AND TRANS & Geranial and neral mixture 3,7-Dimethyl-2,6-octadienal, Geranial and neral mixture CITRAL MIXTURE OF CIS AND TRANS gerznial Citral (cis- and trans- mixture) CITRATHAL 2,6-DIMETHYL-2,6-OCTADIEN-8-AL 2,6-Octadienal,3,7-dimethyl CITRAL(SG) CITRAL TECHN CITRAL EX LITSEA CITRAL LEMILLA MFCD00006997 oiloflemonass citral (cis+trans) b-citral a-citral cis-Citral CITRAL WITH femanumber2303 3,7-Dimethyl-trans-2,6-octadienal Citral,c&t citral,3,7-dimethyl-2,6-octadienal(mixturecisandtrans) 3,7-Dimethyl-2,6-octadienal Citral acis-3,7-dimethyl-2,6-octadienal NCI-C56348 CITRAL, ADE Lemsyn GB cis,trans-Citral 3,7-Dimethyl-1,2,6-octadienal Citral Extra. nat LEMAROME CITRAL 82 GERANIAL AND NERAL LEMOME N DIMETHYLOCTADIENAL (2E)-3,7-Dimethyl-2,6-octadienal lemsyngb geranialdehyde 3,7-Dimethylocta-2,6-dienal 3,7-dimethyl-2,6-octadien-1-al citral b 3,7-Dimethyll-2,6-octadienal CITRAL NATURAL MIXTURE OF CIS A& linmengquan 3,7-Dimethyloctadien-2,6-al-8 EINECS 226-394-6 Citral (cis and trans)

Description	Citral is a monoterpene found in Cymbopogon citratus essential oil, with antihyperalgesic, anti-nociceptive and anti-inflammatory effects[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Campos CA, et al. Anti-hyperalgesic and anti-inflammatory effects of citral with β-cyclodextrin and hydroxypropyl-β-cyclodextrin inclusion complexes in animal models. Life Sci. 2019 Jul 15;229:139-148.

Density	0.9±0.1 g/cm3
Boiling Point	229.0±9.0 °C at 760 mmHg
Melting Point	< -10ºC
Molecular Formula	C₁₀H₁₆O
Molecular Weight	152.233
Flash Point	101.7±0.0 °C
Exact Mass	152.120117
PSA	17.07000
LogP	3.17
Vapour density	5 (vs air)
Vapour Pressure	0.1±0.5 mmHg at 25°C
Index of Refraction	1.457
Storage condition	2-8°C
Stability	Stable. but readily isomerizes. Incompatible with alkalies, strong oxidizing agents, strong acids. Combustible. Air and light sensitive.
Water Solubility	PRACTICALLY INSOLUBLE

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RG5075000

CHEMICAL NAME :: 2,6-Octadienal, 3,7-dimethyl-

CAS REGISTRY NUMBER :: 5392-40-5

BEILSTEIN REFERENCE NO. :: 1721871

LAST UPDATED :: 199801

DATA ITEMS CITED :: 30

MOLECULAR FORMULA :: C10-H16-O

MOLECULAR WEIGHT :: 152.26

WISWESSER LINE NOTATION :: VH1UY1&3Y1&U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Human

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Human - man

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Mammal - pig

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4960 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 460 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6 gm/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 24 gm/kg/10D-I

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Effect on specific coenzyme - CoA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 14952 mg/kg/14D-I

TOXIC EFFECTS :: Liver - other changes Liver - changes in liver weight Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1250 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2500 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 10 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Embryo or Fetus - fetal death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 10 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Effects on Newborn - sex ratio

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

DOSE :: 28 gm/kg

SEX/DURATION :: female 60 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - oogenesis Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

DOSE :: 46 gm/kg

SEX/DURATION :: female 14 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

DOSE :: 46 gm/kg

SEX/DURATION :: female 14 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Fertility - other measures of fertility Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

DOSE :: 27600 mg/kg

SEX/DURATION :: female 60 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Effects on Newborn - live birth index (measured after birth)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 1800 mg/kg

SEX/DURATION :: female 22 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - oogenesis Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 1800 mg/kg

SEX/DURATION :: female 6 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Effects on Newborn - live birth index (measured after birth)

MUTATION DATA

TYPE OF TEST :: DNA repair

TEST SYSTEM :: Bacteria - Bacillus subtilis

DOSE/DURATION :: 2222 ug/disc

REFERENCE :: OIGZDE Osaka-shi Igakkai Zasshi. Journal of Osaka City Medical Association. (Osaka-shi Igakkai, c/o Osaka-shiritsu Daigaku Igakubu, 1-4-54 Asahi-cho, Abeno-ku, Osaka, 545, Japan) V.24- 1975- Volume(issue)/page/year: 34,267,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83184 No. of Facilities: 353 (estimated) No. of Industries: 5 No. of Occupations: 33 No. of Employees: 68051 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83184 No. of Facilities: 12505 (estimated) No. of Industries: 98 No. of Occupations: 84 No. of Employees: 200484 (estimated) No. of Female Employees: 83180 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H317-H319
Precautionary Statements	P280-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R38;R43
Safety Phrases	S24/25-S37
RIDADR	1760
WGK Germany	1
RTECS	RG5075000
Packaging Group	III
Hazard Class	8
HS Code	2932999099

Precursor 10
106-24-1 624-15-7 471-10-3 629-59-4
2687-45-8 5389-87-7 105-86-2 630-19-3
2754-11-2 7549-37-3
DownStream 10
5389-87-7 459-80-3 502-65-8 4501-58-0
78963-10-7 43219-98-3 66407-12-3 432-25-7
5146-66-7 106-44-5

HS Code	2912190090
Summary	2912190090 acyclic aldehydes without other oxygen function。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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