CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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VD5859700
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CHEMICAL NAME :
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Quinuclidine, 2,2,6,6-tetramethyl-, hydrobromide
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CAS REGISTRY NUMBER :
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30015-57-7
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LAST UPDATED :
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199012
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C11-H21-N.Br-H
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MOLECULAR WEIGHT :
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248.25
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WISWESSER LINE NOTATION :
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T66 A B CNTJ B1 B1 D1 D1 &EH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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345 mg/kg
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TOXIC EFFECTS :
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Autonomic Nervous System - ganglion blocker Vascular - BP lowering not characterized in autonomic section
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REFERENCE :
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PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 4,588,1970
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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130 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 35,278,1972
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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52 mg/kg
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TOXIC EFFECTS :
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Autonomic Nervous System - ganglion blocker Vascular - BP lowering not characterized in autonomic section
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REFERENCE :
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PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 4,588,1970
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