Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Subericacidbis(3-sulfo-N-hydroxysuccinimideester)sodiumsalt
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Huang

DC Chemicals Limited
China
Product Name: BS3 Crosslinker
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Bis(sulfosuccinimidyl) suberate sodium salt
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

82436-77-9

82436-77-9 structure

82436-77-9 structure

Name: BS3 Crosslinker
Chemical Name: 1-[8-(2,5-dioxo-3-sulfopyrrolidin-1-yl)oxy-8-oxooctanoyl]oxy-2,5-dioxopyrrolidine-3-sulfonic acid
CAS Number: 82436-77-9
Molecular Formula: C₁₆H₂₀N₂O₁₄S₂
Molecular Weight: 550.447
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-09-17 18:57:11
Modify Date: 2024-01-02 18:29:00
BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	1-[8-(2,5-dioxo-3-sulfopyrrolidin-1-yl)oxy-8-oxooctanoyl]oxy-2,5-dioxopyrrolidine-3-sulfonic acid
Synonyms	Bis(sulfosuccinimidyl)suberate(BS3(Sulfo-DSS)) 3-Pyrrolidinesulfonic acid, 1,1'-[(1,8-dioxo-1,8-octanediyl)bis(oxy)]bis[2,5-dioxo-, sodium salt (1:1) BS(3) Cpd MFCD00054982 1,1'-[(1,8-dioxo-1,8-octanediyl)bis(oxy)]bis(2,5-dioxo-3-pyrrolidinesulfonic acid) Bis(sulfosuccinimidyl) suberate sodium salt BSSIS bis(sulfosuccinimidyl)suberate Disulfosuccinimidyl suberate Sodium 1-({8-[(2,5-dioxo-3-sulfo-1-pyrrolidinyl)oxy]-8-oxooctanoyl}oxy)-2,5-dioxo-3-pyrrolidinesulfonate

Description	BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Melting Point	>300°C
Molecular Formula	C₁₆H₂₀N₂O₁₄S₂
Molecular Weight	550.447
Exact Mass	550.017517
PSA	255.69000
Appearance	powder
Storage condition	−20°C
Water Solubility	H2O: 10 mg/mL

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Hazard Codes	Xi
Risk Phrases	R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	-