BS3 Crosslinker
BS3 Crosslinker structure
|
Common Name | BS3 Crosslinker | ||
|---|---|---|---|---|
| CAS Number | 82436-77-9 | Molecular Weight | 550.447 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H20N2O14S2 | Melting Point | >300°C | |
| MSDS | USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of BS3 CrosslinkerBS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| Name | 1-[8-(2,5-dioxo-3-sulfopyrrolidin-1-yl)oxy-8-oxooctanoyl]oxy-2,5-dioxopyrrolidine-3-sulfonic acid |
|---|---|
| Synonym | More Synonyms |
| Description | BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
| References |
| Melting Point | >300°C |
|---|---|
| Molecular Formula | C16H20N2O14S2 |
| Molecular Weight | 550.447 |
| Exact Mass | 550.017517 |
| PSA | 255.69000 |
| Appearance of Characters | powder |
| Storage condition | −20°C |
| Water Solubility | H2O: 10 mg/mL |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | - |
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| Bis(sulfosuccinimidyl)suberate(BS3(Sulfo-DSS)) |
| 3-Pyrrolidinesulfonic acid, 1,1'-[(1,8-dioxo-1,8-octanediyl)bis(oxy)]bis[2,5-dioxo-, sodium salt (1:1) |
| BS(3) Cpd |
| MFCD00054982 |
| 1,1'-[(1,8-dioxo-1,8-octanediyl)bis(oxy)]bis(2,5-dioxo-3-pyrrolidinesulfonic acid) |
| Bis(sulfosuccinimidyl) suberate sodium salt |
| BSSIS |
| bis(sulfosuccinimidyl)suberate |
| Disulfosuccinimidyl suberate |
| Sodium 1-({8-[(2,5-dioxo-3-sulfo-1-pyrrolidinyl)oxy]-8-oxooctanoyl}oxy)-2,5-dioxo-3-pyrrolidinesulfonate |