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80434-82-8

80434-82-8 structure
80434-82-8 structure
  • Name: 20-hydroxy-20-oxoleukotriene B4
  • Chemical Name: 20-hydroxy-20-oxo-leukotriene B4
  • CAS Number: 80434-82-8
  • Molecular Formula: C20H30O6
  • Molecular Weight: 366.449
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2018-06-28 07:31:23
  • Modify Date: 2024-01-10 00:50:11
  • 20-Carboxy-Leukotriene B4 (20-COOH LTB4) is a metabolite of Leukotriene B4 (LTB4; HY-107608). 20-Carboxy-Leukotriene B4 binds to the BLT1 receptor with high affinity. 20-Carboxy-Leukotriene B4 inhibits LTB4-mediated neutrophil responses (migration, degranulation, leukotriene biosynthesis)[1].
Name 20-hydroxy-20-oxo-leukotriene B4
Synonyms (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxy-6,8,10,14-icosatetraenedioic acid
20-carboxy-LTB4
20-hydroxy-20-oxoleukotriene B4
5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid
6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)-
5,12-Dihydroxy-delta5,8,11,14-eicosapolyendioic acid
20-COOH-LTB4
(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid
20-carboxyleukotriene B4
20-COOH-Leukotriene B4
MFCD00065857
Description 20-Carboxy-Leukotriene B4 (20-COOH LTB4) is a metabolite of Leukotriene B4 (LTB4; HY-107608). 20-Carboxy-Leukotriene B4 binds to the BLT1 receptor with high affinity. 20-Carboxy-Leukotriene B4 inhibits LTB4-mediated neutrophil responses (migration, degranulation, leukotriene biosynthesis)[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Anne-Sophie Archambault, et al. 20-Hydroxy- and 20-carboxy-leukotriene (LT) B4 downregulate LTB4 -mediated responses of human neutrophils and eosinophils. J Leukoc Biol. 2019 Jun;105(6):1131-1142.  

Density 1.2±0.1 g/cm3
Boiling Point 588.3±50.0 °C at 760 mmHg
Molecular Formula C20H30O6
Molecular Weight 366.449
Flash Point 323.6±26.6 °C
Exact Mass 366.204254
PSA 115.06000
LogP 2.02
Vapour Pressure 0.0±3.7 mmHg at 25°C
Index of Refraction 1.548
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H315-H319-H335
Precautionary Statements P210-P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes F,Xi
Risk Phrases 11-36/37/38
Safety Phrases 16-26-36
RIDADR UN 1170 3/PG 2

Chemsrc provides CAS#:80434-82-8 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 80434-82-8 | Chemsrc address: https://m.chemsrc.com/en/baike/1031598.html

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