322-35-0

322-35-0 structure

Name: 2-Amino-3-hydroxy-2'-(2,3,4-trihydroxybenzyl)propionohydrazide
Chemical Name: benserazide
CAS Number: 322-35-0
Molecular Formula: C₁₀H₁₅N₃O₅
Molecular Weight: 257.24300
Catalog: API Nervous system medication Anti-shock palsy
Create Date: 2018-03-09 08:00:00
Modify Date: 2025-08-29 08:16:36
Benserazide is a PKM2 inhibitor. Benserazide directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide can be used for the research of melanoma[1].

Name	benserazide
Synonyms	bensarazide Benseraszide Ro 4-4602 Benserazida DL-Seryltrihydroxybenzylhydrazine MFCD00242633 2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide Serazide Benserazidum

Description	Benserazide is a PKM2 inhibitor. Benserazide directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide can be used for the research of melanoma[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Zhou Y, et al. Benserazide is a novel inhibitor targeting PKM2 for melanoma treatment. Int J Cancer. 2020 Jul 1;147(1):139-151.

TOXIC EFFECTS :: Behavioral - ataxia Kidney, Ureter, Bladder - other changes in urine composition Musculoskeletal - other changes

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 66,201,1982 ** REPRODUCTIVE DATA **

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 66,201,1982

HS Code	2928000090
Summary	2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%