6292-62-2
6292-62-2 structure
- Name: Benzonitrile,4,4'-(1,2-ethenediyl)bis-
- Chemical Name: 4,4'-Stilbenedicarbonitrile
- CAS Number: 6292-62-2
- Molecular Formula: C16H10N2
- Molecular Weight: 230.26
- Catalog: Research Areas Infection
- Create Date: 2016-10-22 23:32:07
- Modify Date: 2025-08-25 12:03:13
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(E/Z)-4,4'-Dicyanostilbene is the inactive isomer of 4,4'-Dicyanostilbene (HY-W112166A), and can be used as an experimental control. 4,4'-Dicyanostilbene (compound 43) is a potent antimalarial agent against the Dd2 strain, with an EC50 of 27 nM. 4,4'-Dicyanostilbene exhibits in vivo efficacy against methicillin-resistant Staphylococcus aureus (MRSA)[1].
| Name | 4,4'-Stilbenedicarbonitrile |
|---|---|
| Synonyms |
stilbene-4,4'-dicarbonitrile
4,4'-Dicyan-stilben 4,4'-Dicyanostilben p,p'-dicyanostilbene |
| Description | (E/Z)-4,4'-Dicyanostilbene is the inactive isomer of 4,4'-Dicyanostilbene (HY-W112166A), and can be used as an experimental control. 4,4'-Dicyanostilbene (compound 43) is a potent antimalarial agent against the Dd2 strain, with an EC50 of 27 nM. 4,4'-Dicyanostilbene exhibits in vivo efficacy against methicillin-resistant Staphylococcus aureus (MRSA)[1]. |
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| Related Catalog | |
| References |
| Density | 1.17g/cm3 |
|---|---|
| Boiling Point | 445ºC at 760 mmHg |
| Molecular Formula | C16H10N2 |
| Molecular Weight | 230.26 |
| Flash Point | 218.6ºC |
| Exact Mass | 230.08400 |
| PSA | 47.58000 |
| LogP | 3.60036 |
| Index of Refraction | 1.63 |
|
~0%
6292-62-2 |
| Literature: Maas, Gerhard; Seitz, Juergen Tetrahedron Letters, 2001 , vol. 42, # 35 p. 6137 - 6140 |
|
~%
6292-62-2 |
| Literature: Russell,G.A. et al. Journal of the American Chemical Society, 1962 , vol. 84, p. 2652 - 2653 |
|
~12%
6292-62-2 |
| Literature: Jawdosiuk, Mikolaj; Uminski, Maciej; Kmiotek-Skarzynska, Irena; Makasza, Mieczyslaw Polish Journal of Chemistry, 1981 , vol. 55, # 6 p. 1309 - 1320 |
|
~%
6292-62-2 |
| Literature: Feuer,H.; Friedman,H. Journal of Organic Chemistry, 1975 , vol. 40, # 2 p. 187 - 190 |
|
~%
6292-62-2 |
| Literature: Bergmann,E.D.; Solomonovici,A. Synthesis, 1970 , p. 183 - 189 |
|
~%
6292-62-2 |
| Literature: Feuer,H.; Friedman,H. Journal of Organic Chemistry, 1975 , vol. 40, # 2 p. 187 - 190 |
|
~%
Detail
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| Literature: Tomioka, Hideo; Tabayashi, Kazuo; Ozaki, Yasuji; Izawa, Yasuji Tetrahedron, 1985 , vol. 41, # 8 p. 1435 - 1440 |
| Precursor 8 | |
|---|---|
| DownStream 1 | |
