Benzonitrile,4,4'-(1,2-ethenediyl)bis-

Modify Date: 2023-01-21 11:17:05

Benzonitrile,4,4'-(1,2-ethenediyl)bis- Structure
Benzonitrile,4,4'-(1,2-ethenediyl)bis- structure
Common Name Benzonitrile,4,4'-(1,2-ethenediyl)bis-
CAS Number 6292-62-2 Molecular Weight 230.26
Density 1.17g/cm3 Boiling Point 445ºC at 760 mmHg
Molecular Formula C16H10N2 Melting Point N/A
MSDS N/A Flash Point 218.6ºC

 Use of Benzonitrile,4,4'-(1,2-ethenediyl)bis-


(E/Z)-4,4'-Dicyanostilbene is the inactive isomer of 4,4'-Dicyanostilbene (HY-W112166A), and can be used as an experimental control. 4,4'-Dicyanostilbene (compound 43) is a potent antimalarial agent against the Dd2 strain, with an EC50 of 27 nM. 4,4'-Dicyanostilbene exhibits in vivo efficacy against methicillin-resistant Staphylococcus aureus (MRSA)[1].

 Names

Name 4,4'-Stilbenedicarbonitrile
Synonym More Synonyms

 Benzonitrile,4,4'-(1,2-ethenediyl)bis- Biological Activity

Description (E/Z)-4,4'-Dicyanostilbene is the inactive isomer of 4,4'-Dicyanostilbene (HY-W112166A), and can be used as an experimental control. 4,4'-Dicyanostilbene (compound 43) is a potent antimalarial agent against the Dd2 strain, with an EC50 of 27 nM. 4,4'-Dicyanostilbene exhibits in vivo efficacy against methicillin-resistant Staphylococcus aureus (MRSA)[1].
Related Catalog
References

[1]. Kyei-Baffour K, et, al. Natural product-inspired aryl isonitriles as a new class of antimalarial compounds against drug-resistant parasites. Bioorg Med Chem. 2020 Oct 1;28(19):115678.  

 Chemical & Physical Properties

Density 1.17g/cm3
Boiling Point 445ºC at 760 mmHg
Molecular Formula C16H10N2
Molecular Weight 230.26
Flash Point 218.6ºC
Exact Mass 230.08400
PSA 47.58000
LogP 3.60036
Index of Refraction 1.63

 Synonyms

stilbene-4,4'-dicarbonitrile
4,4'-Dicyan-stilben
4,4'-Dicyanostilben
p,p'-dicyanostilbene