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129-16-8

129-16-8 structure
129-16-8 structure

Name merbromin
Synonyms Broept
flavurol
Marbromin
Emcerol
Mercury dibromofluorescein disodium salt
gynochrome
MFCD00013081
mercurome
Chromine
domf
Ekakrome
EINECS 204-933-6
Description Merbromin is a xanthene dye.
Related Catalog
Melting Point ≥300 °C
Molecular Formula C20H10Br2HgNa2O6
Molecular Weight 752.67
PSA 113.63000
LogP 3.59240
Stability Stable. Incompatible with strong oxidizing agents, strong acids.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LM5250000
CHEMICAL NAME :
Fluorescein, 2',7'-dibromo-4'-(hydroxymercurio)-, disodium salt
CAS REGISTRY NUMBER :
129-16-8
LAST UPDATED :
199710
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C20-H8-Br2-Hg-O6.2Na
MOLECULAR WEIGHT :
750.67
WISWESSER LINE NOTATION :
T C666 BO EVJ D-HG-Q FE IR BVQ& LE MQ &-NA- 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
15 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory stimulation

MUTATION DATA

TYPE OF TEST :
Sex chromosome loss and nondisjunction
TEST SYSTEM :
Yeast - Saccharomyces cerevisiae
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 31,97,1979 *** REVIEWS *** TOXICOLOGY REVIEW SDGTB3 Seminars in Drug Treatment. (New York, NY) V.1-3, 1971-74. Discontinued. Volume(issue)/page/year: 1,177,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO MERCURY, ARYL AND INORGANIC-air:CL 0.1 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 44650 No. of Facilities: 586 (estimated) No. of Industries: 5 No. of Occupations: 10 No. of Employees: 7896 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 44650 No. of Facilities: 372 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 5294 (estimated) No. of Female Employees: 3955 (estimated)
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H300 + H310 + H330-H373-H410
Precautionary Statements P260-P273-P280-P301 + P310 + P330-P302 + P352 + P310-P304 + P340 + P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T+:Verytoxic;N:Dangerous for the environment;
Risk Phrases R26/27/28;R33;R50/53
Safety Phrases S13-S28-S36-S45-S60-S61
RIDADR UN 2025 6.1/PG 2
WGK Germany 3
RTECS LM5250000
Packaging Group II
Hazard Class 6.1(a)
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