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128-57-4

128-57-4 structure
128-57-4 structure
  • Name: Sennoside B
  • Chemical Name: sennoside B
  • CAS Number: 128-57-4
  • Molecular Formula: C42H38O20
  • Molecular Weight: 862.739
  • Catalog: Biochemical Plant extracts
  • Create Date: 2018-08-31 17:03:29
  • Modify Date: 2025-08-21 12:27:29
  • Sennoside B is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia)[1]. Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway[2].
Name sennoside B
Synonyms SennosideB
[9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, (9R,9'S)-
Sennoside B
EINECS 204-895-0
MFCD00151528
(9R,9'S)-5,5'-Bis(β-D-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid
(9R,9'S)-4,4'-Dihydroxy-10,10'-dioxo-5,5'-bis{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid
Description Sennoside B is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia)[1]. Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway[2].
Related Catalog
References

[1]. Rama Reddy NR, et al. Next Generation Sequencing and Transcriptome Analysis Predicts Biosynthetic Pathway of Sennosides from Senna (Cassia angustifolia Vahl.), a Non-Model Plant with Potent Laxative Properties. PLoS One. 2015 Jun 22;10(6):e0129422.

[2]. Chen YC, et al. Sennoside B inhibits PDGF receptor signaling and cell proliferation induced by PDGF-BB in human osteosarcoma cells. Life Sci. 2009 Jun 19;84(25-26):915-22.
Density 1.7±0.1 g/cm3
Boiling Point 1144.8±65.0 °C at 760 mmHg
Molecular Formula C42H38O20
Molecular Weight 862.739
Flash Point 348.6±27.8 °C
Exact Mass 862.195618
PSA 347.96000
LogP 1.88
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.763
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R22
Safety Phrases 22-45
RIDADR NONH for all modes of transport
Precursor  0

DownStream  2

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