Sennoside B structure
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Common Name | Sennoside B | ||
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CAS Number | 128-57-4 | Molecular Weight | 862.739 | |
Density | 1.7±0.1 g/cm3 | Boiling Point | 1144.8±65.0 °C at 760 mmHg | |
Molecular Formula | C42H38O20 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 348.6±27.8 °C |
Use of Sennoside BSennoside B is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia)[1]. Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway[2]. |
Name | sennoside B |
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Synonym | More Synonyms |
Description | Sennoside B is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia)[1]. Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway[2]. |
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Related Catalog | |
References |
Density | 1.7±0.1 g/cm3 |
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Boiling Point | 1144.8±65.0 °C at 760 mmHg |
Molecular Formula | C42H38O20 |
Molecular Weight | 862.739 |
Flash Point | 348.6±27.8 °C |
Exact Mass | 862.195618 |
PSA | 347.96000 |
LogP | 1.88 |
Vapour Pressure | 0.0±0.3 mmHg at 25°C |
Index of Refraction | 1.763 |
Precursor 0 | |
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DownStream 2 | |
The influence of rhein 8-O-β-D-glucopyranoside on the purgative action of sennoside A from rhubarb in mice.
Biol. Pharm. Bull. 35(12) , 2204-8, (2012) Rhubarb is one of the most well-known herbal medicines that constitute daiokanzoto (DKT), which is clinically effective for constipation. Sennoside A is transformed into an active metabolite, rheinant... |
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The influence of glycyrrhiza and antibiotics on the purgative action of sennoside a from Daiokanzoto in mice.
Biol. Pharm. Bull. 34(9) , 1438-42, (2011) Daiokanzoto (DKT), a Kampo medicine that includes the combination of two crude drugs (rhubarb and glycyrrhiza), is clinically effective for constipation. The aim of this study is to clarify the influe... |
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Effects of optimized-SopungSunkiwon on memory impairment and enhancement.
Neurosci. Lett. 491(2) , 93-8, (2011) Optimized-SopungSunkiwon (OSS) is a multi-herbal formula that contains six medicinal herbs from SopungSunkiwon, a traditional medicine used for neurodegenerative disorders. In this study, we investiga... |
SennosideB |
[9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, (9R,9'S)- |
Sennoside B |
EINECS 204-895-0 |
MFCD00151528 |
(9R,9'S)-5,5'-Bis(β-D-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid |
(9R,9'S)-4,4'-Dihydroxy-10,10'-dioxo-5,5'-bis{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid |