7787-20-4

7787-20-4 structure

Name: (-)-Fenchone
Chemical Name: (1R,4S)-fenchone
CAS Number: 7787-20-4
Molecular Formula: C₁₀H₁₆O
Molecular Weight: 152.233
Catalog: Flavors and spices Synthetic spice Ketone fragrance Alicyclic ketone
Create Date: 2018-05-15 08:00:00
Modify Date: 2024-01-03 21:16:53
(-)-Fenchone, a bicyclic monoterpene, is widely distributed in plants and found in essential oils from Thuja occidentalis. (-)-Fenchone is oxidized to 6-endo-hydroxyfenchone, 6-exo-hydroxyfenchone and 10-hydroxyfenchone derivatives by CYP2A6 and CYP2B6 in human liver microsomes with CYP2A6 playing a more important role than CYP2B6[1].

Name	(1R,4S)-fenchone
Synonyms	(1R,4S)-1,3,3-Trimethylbicyclo[2.2.1]heptan-2-one EINECS 232-107-5 MFCD00151104 (1R)-(-)-Fenchone 2-Norbornanone, 1,3,3-trimethyl-, (1R,4S)-(+)- (-)-1,3,3-Trimethyl-2-norbornanone Bicyclo[2.2.1]heptan-2-one, 1,3,3-trimethyl-, (1R,4S)- (+)-FENCHONE (1R,4S)-fenchone

Description	(-)-Fenchone, a bicyclic monoterpene, is widely distributed in plants and found in essential oils from Thuja occidentalis. (-)-Fenchone is oxidized to 6-endo-hydroxyfenchone, 6-exo-hydroxyfenchone and 10-hydroxyfenchone derivatives by CYP2A6 and CYP2B6 in human liver microsomes with CYP2A6 playing a more important role than CYP2B6[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Miyazawa M, et al. Metabolism of (-)-fenchone by CYP2A6 and CYP2B6 in human liver microsomes. Xenobiotica. 2007;37(2):194-204.

Symbol	GHS02
Signal Word	Warning
Hazard Statements	H226
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Risk Phrases	R10
Safety Phrases	S16
RIDADR	UN 1224 3/PG 3
WGK Germany	3
RTECS	RB7875000
Packaging Group	III
Hazard Class	3.0

2217-02-9

~99%

7787-20-4

Literature: Chemical and Pharmaceutical Bulletin, , vol. 59, # 12 p. 1570 - 1573

74163-80-7

~84%

7787-20-4

Literature: Journal of Chemical Research, , # 7 p. 411 - 414

89050-88-4

7787-20-4

Literature: Journal of Photochemistry and Photobiology A: Chemistry, , vol. 218, # 1 p. 41 - 47

18084-01-0

~58%

7787-20-4

131062-94-7

137255-12-0

Literature: Tetrahedron Letters, , vol. 31, # 22 p. 3151 - 3154