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126724-95-6

126724-95-6 structure
126724-95-6 structure
  • Name: Tilifodiolide
  • Chemical Name: (1R,8S)-1-(furan-3-yl)-8-(5-oxo-2H-furan-4-yl)-6,7,8,9-tetrahydro-1H-benzo[e][2]benzofuran-3-one
  • CAS Number: 126724-95-6
  • Molecular Formula: C20H16O5
  • Molecular Weight: 336.34
  • Catalog: Natural product Moss
  • Create Date: 2018-06-11 18:24:48
  • Modify Date: 2025-08-26 08:59:24
  • Tilifodiolide ((-)-Tilifodiolide) is a lactone, which can be isolated from the roots of Salvia tiliaefolia. Tilifodiolide has anti-inflammatory activity in mice model[1].

Name (1R,8S)-1-(furan-3-yl)-8-(5-oxo-2H-furan-4-yl)-6,7,8,9-tetrahydro-1H-benzo[e][2]benzofuran-3-one
Synonyms Naphtho[1,2-c]furan-3(1H)-one, 8-(2,5-dihydro-2-oxo-3-furanyl)-1-(3-furanyl)-6,7,8,9-tetrahydro-, (1R,8S)-
Tilifodiolide
(1R,8S)-1-(3-Furyl)-8-(2-oxo-2,5-dihydro-3-furanyl)-6,7,8,9-tetrahydronaphtho[1,2-c]furan-3(1H)-one
Description Tilifodiolide ((-)-Tilifodiolide) is a lactone, which can be isolated from the roots of Salvia tiliaefolia. Tilifodiolide has anti-inflammatory activity in mice model[1].
Related Catalog
In Vitro Tilifodiolide (200 mg/kg; single dose) shows anti-inflammatory activity in vivo in acetic acid induced-writhing mouse model[1].
References

[1]. González-Chávez MM, Alonso-Castro AJ, Zapata-Morales JR, Arana-Argáez V, Torres-Romero JC, Medina-Rivera YE, Sánchez-Mendoza E, Pérez-Gutiérrez S. Anti-inflammatory and antinociceptive effects of tilifodiolide, isolated from Salvia tiliifolia Vahl (Lamiaceae). Drug Dev Res. 2018 Jun;79(4):165-172.  

Density 1.4±0.1 g/cm3
Boiling Point 577.3±50.0 °C at 760 mmHg
Molecular Formula C20H16O5
Molecular Weight 336.34
Flash Point 303.0±30.1 °C
Exact Mass 336.099762
PSA 65.74000
LogP 1.93
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.641
Hazard Codes Xi
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