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3583-64-0

3583-64-0 structure
3583-64-0 structure
  • Name: Bumadizone
  • Chemical Name: bumadizone
  • CAS Number: 3583-64-0
  • Molecular Formula: C19H22N2O3
  • Molecular Weight: 326.39000
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2018-08-21 18:06:36
  • Modify Date: 2024-01-04 17:09:54
  • Bumadizone is a non-steroidal anti-inflammatory drug (NSAID) and can relieve pain[1].
Name bumadizone
Synonyms Butyramide,N-sec-butyl
(+-)-Buttersaeure-sec-butylamid
2-[(1,2-Diphenylhydrazino)carbonyl]hexanoic acid
Butanamide,N-(1-methylpropyl)
N-(2-Carboxy-hexanoyl)-hydrazobenzol
N-s-Butyl-butyramide
N-sec-butyl-butyramide
N-(2-carboxycaproyl)hydrazobenzene
N-(2-BUTYL)BUTANAMIDE
Bumadizon (14C)
Butylmalonsaeure-N,N'-diphenylmonohydrazid
(+-)-Butylmalonsaeure-mono-<N.N'-diphenyl-hydrazid>
Description Bumadizone is a non-steroidal anti-inflammatory drug (NSAID) and can relieve pain[1].
Related Catalog
In Vitro Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in the chronic inflammatoryconditions.
References

[1]. Samia A Nour, et al. Bumadizone calcium dihydrate microspheres compressed tablets for colon targeting: formulation, optimization and in vivo evaluation in rabbits. Drug Deliv. 2015 May;22(3):286-97.
Density 1.227g/cm3
Boiling Point 487.4ºC at 760mmHg
Molecular Formula C19H22N2O3
Molecular Weight 326.39000
Flash Point 248.6ºC
Exact Mass 326.16300
PSA 69.64000
LogP 4.01070
Index of Refraction 1.628

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OO0623000
CHEMICAL NAME :
Malonic acid, butyl-, mono(1,2-diphenylhydrazide)
CAS REGISTRY NUMBER :
3583-64-0
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H22-N2-O3
MOLECULAR WEIGHT :
326.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1350 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 67,337,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
270 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 67,337,1971
HS Code 2928000090
Precursor  1

DownStream  0

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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