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827031-83-4

827031-83-4 structure
827031-83-4 structure
  • Name: Verubulin
  • Chemical Name: N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine
  • CAS Number: 827031-83-4
  • Molecular Formula: C17H17N3O
  • Molecular Weight: 279.336
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2018-10-18 19:57:13
  • Modify Date: 2024-01-31 17:09:00
  • Verubulin (MPC-6827) is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities, and acts as a promising candidate for the treatment of multiple cancer types[1].

Name N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine
Synonyms Verubulin
4-Quinazolinamine, N-(4-methoxyphenyl)-N,2-dimethyl-
N-(4-Methoxyphenyl)-N,2-dimethyl-4-quinazolinamine
N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine
Description Verubulin (MPC-6827) is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities, and acts as a promising candidate for the treatment of multiple cancer types[1].
Related Catalog
Target

Microtubule[1]

References

[1]. Kasibhatla S, et al. MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps. Cancer Res. 2007 Jun 15;67(12):5865-71.

Density 1.2±0.1 g/cm3
Boiling Point 398.7±38.0 °C at 760 mmHg
Melting Point 86-90 °C
Molecular Formula C17H17N3O
Molecular Weight 279.336
Flash Point 194.9±26.8 °C
Exact Mass 279.137177
PSA 38.25000
LogP 2.02
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.652
Storage condition -20°C
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%