Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3,4-Dihydro-7-hydroxycarbostyril
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 7-hydroxy-3,4-dihydro-1H-quinolin-2-one
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Price: ￥Inquiry/25kg
Purity: 99.0%
Stocking Period: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

22246-18-0

22246-18-0 structure

22246-18-0 structure

Name: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Chemical Name: 7-hydroxy-3,4-dihydro-1H-quinolin-2-one
CAS Number: 22246-18-0
Molecular Formula: C₉H₉NO₂
Molecular Weight: 163.173
Catalog: Pharmaceutical intermediate Heterocyclic compound Quinoline compound
Create Date: 2018-12-12 08:23:18
Modify Date: 2026-06-30 18:32:25
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1].

Name	7-hydroxy-3,4-dihydro-1H-quinolin-2-one
Synonyms	4-dihydro-quinolin-2-one 7-HYDROXY-3,4-DIHYDROCBOSTYRIL 7-HYDROXY-3,4-DIHYDRO-QUINOLIN-2-ONE 7-Hydroxy-3,4-dihydroquinoline-2(1H)-one 7-Hydroxy-3,4-dihydro-2(1H)-chinolinon 7-HYDROXY-3,4-DIHYDRO CBOSTYRYL 7-Hydroxy cbostyril 7-Hydroxy-3,4-dihydrochinolin-2(1H)-on Brexpiprazole Impurity 5 7-HYDROXY-3,4-DIHYDROQUINOLIN-2(1H)-ONE 7-HYDROXY-1,2,3,4-TETRAHYDRO-2-QUINOLINONE 2(1H)-Quinolinone,7-hydroxy, 3,4-dihydro Aripiprazole - Impurity A 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone SynonyMs 7-Hydroxy Cbostyril ipiprazole Impurity A 7-HYDROXY-1,2,3,4-TETRAHYDROQUINOLINE-2-ONE 7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINLINONE ipiprazole Impurity A(3,4-Dihydro-7-hydroxyquinoline-2(1H)-one) 7-Hydroxy-2(1H)-3,4-dihydroquinolinone 7-hydroxy-3,4-dihydroquinolin-2(1H)-one 3,4-Dihydro-7-hydrox 7-Hydroxy-3 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone 7-HYDROXY-3,4-DIHYDROCBOSTYRIL 22-0 4-Dihydro-7-hydroxy-2(1H)-quinolinone 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone ISO 9001：2015 REACH 7-HYDROXY-3,4-DIHYDRO-2(1H)QUINOLINONE//INTERMEDIATE OF IPIPRAZOLE ipiprazole Impurity 13 3,4-Dihydro-7-Hydroxy-2(1H)-Quinlinone 3,4-DIHYDRO-7-HYDROXYCBOSTYRIL 8-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE 7-Hydroxy-3,4-dihydro-2-quinolinone AURORA KA-4813 ipiprazole Impurity A/ ipiprazole Dihydroquinolinone Impurity 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone> 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone 7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE3,4-DIHYDRO-7-HYDROXY-2-(1H)-QUINOLINONE 7-Hydroxy-3,4-dihydro-quinolin-2-one ipiprazole intermediate 7-HYDROXY-2-OXO-3,4-DIHYDROQUINOLINE, IPIPRZAOLE INTERMEDIATE 7-HYDROXY-1,2,3,4-TETRAHYDROQUINOLIN-2-ONE 3,4-Dihydro-7-hydroxy-2(1H)-quinolinon ipiprazole Impurity 21（ipiprazole Impurity A） 7-HYDROXY-3,4-DIHYDRO-2-OXO-(1H)-QUINOLINE 7-Hydroxy-3,4-dihydro-2(H)-quinolinone 7-Hydroxy-2-Oxo-3,4-Dihydroquinoline Intermediate of ipiprazole 7-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone, 7-Hydroxy-3,4-dihydrocbostyril 7-hydroxy-3,4-dihydro-2-quinolinone 7-Hydroxy-3,4-dihydro-2(1H)-quinoL 7-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE 7- hydroxy-3,4- twohydrogen -2(1H)- quinolinone 3,4-Dihydro-7-hydroxycarbostyril 7-hydroxy-3,4-dihydro-2(1H)quinolinone (1H)-7-HYDROXY-3,4-DIHYDRO-2-QUINOLINONE 7-HYDROXY-3, 4-DIHYDRO-2(1H)-QUINLIONE 7-Hydroxy-3,4-dihydro carbostyril ipiprazole Dihydroquinolinone Impurity 7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE 3,4-DIHYDRO-7-HYDROXY-2(1H)-QUINOLINONE /7-HQ MFCD06410891 7-Hydroxy-1,2,3,4-tetrahydro-2-chinolinon 7-Hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline ipiprazole Imp.A 3,4-Dihydro-7-hydroxy-1H-quinolin-2-one 7-Hydroxy-3,4-dihydro-2(1H)-qu

Description	7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
Target	IC50: 183 μM (MAO-A)[1]
In Vitro	7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1].
References	[1]. Meiring L, et al. Inhibition of monoamine oxidase by 3,4-dihydro-2(1H)-quinolinone derivatives. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5498-502.

Density	1.3±0.1 g/cm3
Boiling Point	403.7±45.0 °C at 760 mmHg
Melting Point	233-237 °C
Molecular Formula	C₉H₉NO₂
Molecular Weight	163.173
Flash Point	198.0±28.7 °C
Exact Mass	163.063324
PSA	49.33000
LogP	0.99
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.604

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H317
Precautionary Statements	P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xi: Irritant;Xn: Harmful;
Risk Phrases	R22;R43
Safety Phrases	S36/37
RIDADR	NONH for all modes of transport
HS Code	2933499090

Precursor 8
21261-76-7 50297-40-0 536-90-3 625-36-5
591-27-5 7403-75-0 22246-17-9 103986-96-5
DownStream 8
58196-33-1 129722-12-9 129722-34-5 120004-79-7
1194459-28-3 71130-68-2 952308-47-3 58022-96-1

HS Code	2933790090
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

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