37338-80-0

37338-80-0 structure

Name: orellanine
Chemical Name: 2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one
CAS Number: 37338-80-0
Molecular Formula: C₁₀H₈N₂O₆
Molecular Weight: 252.18
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
Create Date: 2018-06-21 17:04:11
Modify Date: 2024-01-08 20:36:45
Orellanine is a fungal nephrotoxin. Orellanine is also a competitive inhibitor of alkaline phosphatase. Orellanine induces cell death in proximal tubular cells and in ccRCC cells. Orellanine can be used for research of clear cell renal cell carcinoma (ccRCC)[1][2].

Name	2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one
Synonyms	3,3',4,4'-tetrahydroxy-2,2'-bipyridine-1,1'-dioxide Orellanin 2,2'-bipyridine-3,3',4,4'-tetrol-1,1'-dioxide Orellanine 3,3',4,4'-Tetrahydroxy-2,2'-bipyridine-N,N'-dioxide

Description	Orellanine is a fungal nephrotoxin. Orellanine is also a competitive inhibitor of alkaline phosphatase. Orellanine induces cell death in proximal tubular cells and in ccRCC cells. Orellanine can be used for research of clear cell renal cell carcinoma (ccRCC)[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase
References	[1]. Lyons MJ, et al. Orellanine: From Fungal Origin to a Potential Future Cancer Treatment. J Nat Prod. 2023 Jun 23;86(6):1620-1631. [2]. Buvall L, et al. Orellanine specifically targets renal clear cell carcinoma. Oncotarget. 2017 Jul 25;8(53):91085-91098.

HS Code	2933399090

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%