443144-26-1
443144-26-1 structure
- Name: EMD-281014
- Chemical Name: 7-[4-[2-(4-fluorophenyl)ethyl]piperazine-1-carbonyl]-1H-indole-3-carbonitrile
- CAS Number: 443144-26-1
- Molecular Formula: C22H21FN4O
- Molecular Weight: 376.42700
- Create Date: 2016-11-01 03:42:36
- Modify Date: 2024-01-21 16:20:00
-
EMD-281014 is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels.
| Name | 7-[4-[2-(4-fluorophenyl)ethyl]piperazine-1-carbonyl]-1H-indole-3-carbonitrile |
|---|---|
| Synonyms | Pruvanserin |
| Density | 1.33g/cm3 |
|---|---|
| Boiling Point | 605.7ºC at 760mmHg |
| Molecular Formula | C22H21FN4O |
| Molecular Weight | 376.42700 |
| Flash Point | 320.1ºC |
| Exact Mass | 376.17000 |
| PSA | 63.13000 |
| LogP | 3.05498 |