443144-27-2
443144-27-2 structure
- Name: EMD 281014 hydrochloride
- Chemical Name: 7-[4-[2-(4-fluorophenyl)ethyl]piperazine-1-carbonyl]-1H-indole-3-carbonitrile,hydrochloride
- CAS Number: 443144-27-2
- Molecular Formula: C22H22ClFN4O
- Molecular Weight: 412.88800
- Create Date: 2016-10-05 07:48:50
- Modify Date: 2025-08-29 21:46:39
-
EMD-281014 hydrochloride is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels.
| Name | 7-[4-[2-(4-fluorophenyl)ethyl]piperazine-1-carbonyl]-1H-indole-3-carbonitrile,hydrochloride |
|---|---|
| Synonyms |
Pruvanserin hydrochloride
Pruvanserin HCl UNII-AWA682DH9Z PHP 501 trifluoroacetate |
| Molecular Formula | C22H22ClFN4O |
|---|---|
| Molecular Weight | 412.88800 |
| Exact Mass | 412.14700 |
| PSA | 63.13000 |
| LogP | 3.85698 |