- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 1-Methyl-2-undecylquinolin-4(1H)
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Huang
- DC Chemicals Limited
- China
- Product Name: 1-Methyl-2-undecyl-4(1H)-quinolone
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 1-Methyl-2-undecyl-1,4-dihydroquinoline-4-one
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
59443-02-6
59443-02-6 structure
- Name: 1-Methyl-2-undecylquinolin-4(1H)-one
- Chemical Name: 1-methyl-2-undecylquinolin-4-one
- CAS Number: 59443-02-6
- Molecular Formula: C21H31NO
- Molecular Weight: 313.477
- Catalog: Natural product Alkaloid
- Create Date: 2016-08-11 06:49:17
- Modify Date: 2024-01-10 14:41:02
-
1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS[1][2].
| Name | 1-methyl-2-undecylquinolin-4-one |
|---|---|
| Synonyms |
1-Methyl-2-undecyl-4(1H)-quinolone
1-Methyl-2-undecyl-4(1H)-quinolinone 4(1H)-Quinolinone, 1-methyl-2-undecyl- 1-methyl-2-undecyl-1H-quinolin-4-one |
| Description | 1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS[1][2]. |
|---|---|
| Related Catalog | |
| Target |
MAO-B:15.3 μM (IC50) MAO-B:9.91 μM (Ki) |
| In Vitro | 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity[2]. |
| References |
[1]. Toshiya K, et al. Isolation and Structure Elucidation of Three Quinolone |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 419.9±45.0 °C at 760 mmHg |
| Molecular Formula | C21H31NO |
| Molecular Weight | 313.477 |
| Flash Point | 141.0±18.1 °C |
| Exact Mass | 313.240570 |
| PSA | 22.00000 |
| LogP | 7.16 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.519 |
| Hazard Codes | Xi |
|---|
|
~%
59443-02-6 |
| Literature: Tang, Yuan-Qing; Feng, Xiao-Zhang; Huang, Liang Phytochemistry, 1996 , vol. 43, # 3 p. 719 - 722 |
|
~%
59443-02-6 |
| Literature: Coppola, Gary M. Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 491 - 494 |
