Shanghai Nianxing Industrial Co., Ltd
China
Product Name: carazolol
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: carazolol
Price: ￥1718.0/10mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Carazolol
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

57775-29-8

57775-29-8 structure

57775-29-8 structure

Name: carazolol
Chemical Name: carazolol hcl
CAS Number: 57775-29-8
Molecular Formula: C₁₈H₂₂N₂O₂
Molecular Weight: 298.38
Catalog: analytical chemistry Standard Forensic and veterinary standards
Create Date: 2018-10-02 16:32:44
Modify Date: 2025-08-27 13:03:17
Carazolol is a β1/β2 adrenoceptor antagonist of high potency used in the research of hypertension. Carazolol is also a potent, selective β3-adrenoceptor agonist[1].

Name	carazolol hcl
Synonyms	Conduction 1-(9H-Carbazol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol 1-(9H-carbazol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol carazolol CARAZOLOL HYDROCHLORIDE 1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)-2-propanol EINECS 260-945-1 1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol suacron MFCD03428052 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-[(1-methylethyl)amino]- Carazololum Conducton

Description	Carazolol is a β1/β2 adrenoceptor antagonist of high potency used in the research of hypertension. Carazolol is also a potent, selective β3-adrenoceptor agonist[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	β1 adrenoceptor β2 adrenoceptor β3 adrenoceptor
In Vivo	Carazolol (0.01 mg/kg; i.m.; once) shows no significant side effects[2]. Animal Model: Kivircik sheeps, 25-45 kg, nonpregnant[2] Dosage: 0.01 mg/kg Administration: Intramuscular injection, once Result: Urea, creatinin, ALT, ALP, GGT, LDH, Ca, P, T.Protein, Mg, Cu levels in blood serum parameters were found to be in normal level however serum Fe, Zn levels were decreased.
References	[1]. A Méjean, et al. Carazolol: a potent, selective beta 3-adrenoceptor agonist. Eur J Pharmacol. 1995 Nov 30;291(3):359-66. [2]. Remzi Gonul, et al. Effects of carazolol on electrocadiographic and trace element status in sheeps. Insights Vet Sci. 2018; 2: 001- 004.

Density	1.2±0.1 g/cm3
Boiling Point	531.2±40.0 °C at 760 mmHg
Melting Point	133-137 °C
Molecular Formula	C₁₈H₂₂N₂O₂
Molecular Weight	298.38
Flash Point	275.1±27.3 °C
Exact Mass	298.168121
PSA	57.28000
LogP	3.59
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.652

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UA8685000

CHEMICAL NAME :: 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-((1-methylethyl)amino)-

CAS REGISTRY NUMBER :: 57775-29-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H22-N2-O2

MOLECULAR WEIGHT :: 298.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 10 ug/kg

SEX/DURATION :: female 16 week(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - parturition

REFERENCE :: THGNBO Theriogenology. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1974- Volume(issue)/page/year: 20,191,1983

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S26
RIDADR	NONH for all modes of transport
RTECS	UA8685000
HS Code	2933990090

Precursor 0
DownStream 2
78859-34-4 78859-33-3

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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