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123-99-9

123-99-9 structure
123-99-9 structure
  • Name: Azelaic acid
  • Chemical Name: azelaic acid
  • CAS Number: 123-99-9
  • Molecular Formula: C9H16O4
  • Molecular Weight: 188.221
  • Catalog: API Special medicine Dermatology medication
  • Create Date: 2018-05-27 08:00:00
  • Modify Date: 2024-01-02 15:21:22
  • Azelaic acid is an organic compound produced by the ozonolysis of oleic acid; component of a number of hair and skin conditioners.

Name azelaic acid
Synonyms Skinoren
AZALEIC ACID
Azelaate
3,4-Dimethoxybenzaldehyde
Nonanedioic acid
Azelaic acid
UNII-F2VW3D43YT
AZELAIC ACID/NONANEDIOIC ACID
Barasertib
AZELAIC ACID FOR SYNTHESIS
INH 34
Azelex
Azelaicacid
Finaceae
lepargylic acid
1,7-HEPTANE DICARBONIC ACID
1,7-HEPTANEDICARBOXYLIC
AZD1152-HQPA
Azelainic acid
HEPTANE-1,7-DICARBOXYLIC ACID
Azalaic Acid
AZELAIC ACID( MICRONIZED )
EINECS 204-669-1
anchoic acid
1,7-Heptanedicarboxylic acid
MFCD00004432
Description Azelaic acid is an organic compound produced by the ozonolysis of oleic acid; component of a number of hair and skin conditioners.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Jung HW, et al. Priming in systemic plant immunity. Science. 2009 Apr 3;324(5923):89-91.

[2]. Liu RH, et al. Azelaic acid in the treatment of papulopustular rosacea: a systematic review of randomized controlled trials. Arch Dermatol. 2006 Aug;142(8):1047-52.

Density 1.1±0.1 g/cm3
Boiling Point 286 ºC (100 mmHg)
Melting Point 98-103 ºC
Molecular Formula C9H16O4
Molecular Weight 188.221
Flash Point 215 ºC
Exact Mass 188.104858
PSA 74.60000
LogP 1.33
Vapour density 6.5 (vs air)
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.475
Stability Stable. Combustible. Incompatible with bases, strong oxidizing agents. Readily biodegrades in soil and water with >70% DOC reduction after 28 days.
Water Solubility 2.4 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CM1980000
CHEMICAL NAME :
Azelaic acid
CAS REGISTRY NUMBER :
123-99-9
BEILSTEIN REFERENCE NO. :
1101094
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C9-H16-O4
MOLECULAR WEIGHT :
188.25
WISWESSER LINE NOTATION :
QV7VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
EMERY* Emery Industries, Inc., Data Sheets. (4900 Este Ave., Cincinnati, OH 45232) Volume(issue)/page/year: S3B,-,1964
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
EMERY* Emery Industries, Inc., Data Sheets. (4900 Este Ave., Cincinnati, OH 45232) Volume(issue)/page/year: S3B,-,1964 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD-A067-313 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83495 No. of Facilities: 170 (estimated) No. of Industries: 8 No. of Occupations: 11 No. of Employees: 1676 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83495 No. of Facilities: 3427 (estimated) No. of Industries: 35 No. of Occupations: 42 No. of Employees: 34469 (estimated) No. of Female Employees: 7576 (estimated)
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS CM1980000
HS Code 2917139000
HS Code 2917139000
Summary 2917139000 azelaic acid, sebacic acid, their salts and esters VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%