Name | 10-Nitrooleic Acid |
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Synonyms | 10-Nitro Oleic Acid |
Description | 10-Nitrooleic acid (CXA-10), a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles[1]. |
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Related Catalog | |
In Vitro | 10-Nitrooleic acid (5-25 μM; mouse keratinocytes) regulates expression of HO-1, hsp27, hsp70, Cox-2, and the glutathione-S-transferases GSTA1-2, GSTA3 and GSTA4 in a generally similar manner[1]. 10-Nitrooleic acid (10 μM; 0-6 hours) upregulates HO-1 protein in time- and concentration-dependent manners. 10-Nitrooleic acid also upregulates protein expression for Cox-2, hsp27, hsp70[1]. |
References |
Molecular Formula | C18H33NO4 |
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Molecular Weight | 327.46 |
Exact Mass | 327.24100 |
PSA | 83.12000 |
LogP | 6.23610 |
~% 875685-46-4 |
Literature: Gorczynski, Michael J.; Huang, Jinming; King, S. Bruce Organic Letters, 2006 , vol. 8, # 11 p. 2305 - 2308 |
Precursor 1 | |
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DownStream 0 |