10-Nitro Oleic Acid

Modify Date: 2024-01-02 21:34:14

10-Nitro Oleic Acid structure	Common Name	10-Nitro Oleic Acid
	CAS Number	875685-46-4	Molecular Weight	327.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₃₃NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 10-Nitro Oleic Acid

10-Nitrooleic acid (CXA-10), a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles[1].

Name	10-Nitrooleic Acid
Synonym	More Synonyms

Description	10-Nitrooleic acid (CXA-10), a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	10-Nitrooleic acid (5-25 μM; mouse keratinocytes) regulates expression of HO-1, hsp27, hsp70, Cox-2, and the glutathione-S-transferases GSTA1-2, GSTA3 and GSTA4 in a generally similar manner[1]. 10-Nitrooleic acid (10 μM; 0-6 hours) upregulates HO-1 protein in time- and concentration-dependent manners. 10-Nitrooleic acid also upregulates protein expression for Cox-2, hsp27, hsp70[1].
References	[1]. Garner RM, Mould DR, Chieffo C, Jorkasky DK. Pharmacokinetic and Pharmacodynamic Effects of Oral CXA-10, a Nitro Fatty Acid, After Single and Multiple Ascending Doses in Healthy and Obese Subjects. Clin Transl Sci. 2019;12(6):667-676. [2]. Zheng R, et al. Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid. Free Radic Biol Med. 2014;67:1-9.

Molecular Formula	C₁₈H₃₃NO₄
Molecular Weight	327.46
Exact Mass	327.24100
PSA	83.12000
LogP	6.23610

2-hydroxy-1-nitrononane structure

2-hydroxy-1-nit...

CAS#:4013-87-0

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10-Nitro Oleic Acid Structure

10-Nitro Oleic Acid

CAS#:875685-46-4

Literature: Gorczynski, Michael J.; Huang, Jinming; King, S. Bruce Organic Letters, 2006 , vol. 8, # 11 p. 2305 - 2308

Precursor 1
CAS#:4013-87-0 2-hydroxy-1-nit...
DownStream 0

10-Nitro Oleic Acid

Shanghai Nianxing Industrial Co., Ltd
China
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China
Product Name: 10-Nitrooleic acid
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 10-Nitro Oleic Acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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