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842-15-9

842-15-9 structure
842-15-9 structure

Name 2-Naphthylamine-6,8-Disulfonic Acid Monopotassium Salt
Synonyms 7-amino-1,3-naphthalenedisulfonic acid monopotassium salt
EINECS 212-669-8
MFCD00064177
Description 2-Naphthylamine-6,8-disulfonic acid potassium is chemical that can be used for preparing dyestuff, medicine, agricultural chemicals etc[1].
Related Catalog
In Vitro 2-Naphthylamine-6,8-disulfonic acid potassium (compound 20) can inhibit human immunodeficiency virus HIV-1 and HIV-2 by 11% and 13.6% at a concentration of 1369 μM, respectively[1]. 2-Naphthylamine-6,8-disulfonic acid potassium (ANDS) can directly analyze polyglycolic pyrophosphate-linked oligosaccharides in cell cultures and tissues[3]. Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).Labeling oligosaccharides[3]: 1. Prepared 0.15 M ANDS with 15% (v/v) acetic acid. 2. Prepare 1M solution of sodium cyanoborohydride in dimethyl sulfoxide (DMSO). 3. Add 5 μL ANDS reagent (1 μL if sample is below 200 pmol) to the sample. 4. Add 5 μL sodium cyanoborohydride solution (1 μL if sample is below 200 pmol) to the sample. 5. After mixing, the reaction was briefly centrifuged and allowed to dry for 18 hours at 37 °C.
References

[1]. G T Tan, et al. Potential anti-AIDS naphthalenesulfonic acid derivatives. Synthesis and inhibition of HIV-1 induced cytopathogenesis and HIV-1 and HIV-2 reverse transcriptase activities. J Med Chem. 1992 Dec 25;35(26):4846-53.

[2]. K B Lee, et al. A new method for sequencing linear oligosaccharides on gels using charged, fluorescent conjugates. Carbohydr Res. 1991 Jul 18;214(1):155-68.

[3]. Ningguo Gao, et al. Fluorophore-assisted carbohydrate electrophoresis: a sensitive and accurate method for the direct analysis of dolichol pyrophosphate-linked oligosaccharides in cell cultures and tissues. Methods. 2005 Apr;35(4):323-7.

[4]. Preparation method of 2-naphthylamine 6,8 disulfonic acid. CN102295585A.

Density 0.881 g/mL at 25 °C(lit.)
Boiling Point 159-161 °C(lit.)
Melting Point −69 °C(lit.)
Molecular Formula C10H8KNO6S2
Molecular Weight 341.40200
Flash Point 107 °F
Exact Mass 340.94300
PSA 154.35000
LogP 3.31560
Index of Refraction n20/D 1.425(lit.)
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
WGK Germany 3
HS Code 2921450090
HS Code 2921450090
Summary 2921450090 1-naphthylamine (α-naphthylamine), 2-naphthylamine (β-naphthylamine) and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%