148031-34-9

148031-34-9 structure

Name: Eptifibatide Acetate
Chemical Name: Eptifibatide
CAS Number: 148031-34-9
Molecular Formula: C₃₅H₄₉N₁₁O₉S₂
Molecular Weight: 831.962
Catalog: Biochemical Peptide
Create Date: 2018-03-31 08:00:00
Modify Date: 2024-01-02 12:50:23
Eptifibatide, also co-promoted by Schering-Plough/Essex, is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.

Name	Eptifibatide
Synonyms	n6-(aminoiminomethyl)-n2-(3-mercapto-1-oxopropyl-l-lysylglycyl-l-a-aspartyl-l-tryptophyl-l-prolyl-l-cysteinamide 7H-Pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosine-17-acetic acid, 3-(aminocarbonyl)-11-[4-[(aminoiminomethyl)amino]butyl]docosahydro-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxo- Mpr-Harg-Gly-Asp-Trp-Pro-Cys-NH2,( Disulfide Bridge:1-7) EFTIFIBATIDE MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2 MFCD05662245 [11-(4-Carbamimidamidobutyl)-3-carbamoyl-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosin-17-yl]acetic acid Mpr-Harg-Gly-Asp-Trp-Pro-Cys-NH2,( Disulfide Bridg on Mpr and Cys) Eptifitide INTEGRELIN Eptifibatide Acetate 7H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosine-17-acetic acid, 3-(aminocarbonyl)-11-[4-[(diaminomethylene)amino]butyl]docosahydro-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxo-

Hazard Codes	Xi,Xn
Risk Phrases	R36/37/38:Irritating to eyes, respiratory system and skin . R22:Harmful if swallowed.
Safety Phrases	S26-S36/37/39
RIDADR	UN 2811 6.1/PG 3