Eptifibatide Acetate structure
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Common Name | Eptifibatide Acetate | ||
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CAS Number | 148031-34-9 | Molecular Weight | 831.962 | |
Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C35H49N11O9S2 | Melting Point | 92-98 °C | |
MSDS | Chinese | Flash Point | N/A |
Use of Eptifibatide AcetateEptifibatide, also co-promoted by Schering-Plough/Essex, is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market. |
Name | Eptifibatide |
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Synonym | More Synonyms |
Density | 1.6±0.1 g/cm3 |
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Melting Point | 92-98 °C |
Molecular Formula | C35H49N11O9S2 |
Molecular Weight | 831.962 |
Exact Mass | 831.315613 |
PSA | 374.49000 |
LogP | -4.84 |
Index of Refraction | 1.735 |
Storage condition | 2-8°C |
Hazard Codes | Xi,Xn |
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Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . R22:Harmful if swallowed. |
Safety Phrases | S26-S36/37/39 |
RIDADR | UN 2811 6.1/PG 3 |
n6-(aminoiminomethyl)-n2-(3-mercapto-1-oxopropyl-l-lysylglycyl-l-a-aspartyl-l-tryptophyl-l-prolyl-l-cysteinamide |
7H-Pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosine-17-acetic acid, 3-(aminocarbonyl)-11-[4-[(aminoiminomethyl)amino]butyl]docosahydro-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxo- |
Mpr-Harg-Gly-Asp-Trp-Pro-Cys-NH2,( Disulfide Bridge:1-7) |
EFTIFIBATIDE |
MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2 |
MFCD05662245 |
[11-(4-Carbamimidamidobutyl)-3-carbamoyl-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosin-17-yl]acetic acid |
Mpr-Harg-Gly-Asp-Trp-Pro-Cys-NH2,( Disulfide Bridg on Mpr and Cys) |
Eptifitide |
INTEGRELIN |
Eptifibatide Acetate |
7H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosine-17-acetic acid, 3-(aminocarbonyl)-11-[4-[(diaminomethylene)amino]butyl]docosahydro-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxo- |