Eptifibatide Acetate

Modify Date: 2024-01-02 12:50:23

Eptifibatide Acetate Structure
Eptifibatide Acetate structure
Common Name Eptifibatide Acetate
CAS Number 148031-34-9 Molecular Weight 831.962
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C35H49N11O9S2 Melting Point 92-98 °C
MSDS Chinese Flash Point N/A

 Use of Eptifibatide Acetate


Eptifibatide, also co-promoted by Schering-Plough/Essex, is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.

 Names

Name Eptifibatide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Melting Point 92-98 °C
Molecular Formula C35H49N11O9S2
Molecular Weight 831.962
Exact Mass 831.315613
PSA 374.49000
LogP -4.84
Index of Refraction 1.735
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi,Xn
Risk Phrases R36/37/38:Irritating to eyes, respiratory system and skin . R22:Harmful if swallowed.
Safety Phrases S26-S36/37/39
RIDADR UN 2811 6.1/PG 3

 Synonyms

n6-(aminoiminomethyl)-n2-(3-mercapto-1-oxopropyl-l-lysylglycyl-l-a-aspartyl-l-tryptophyl-l-prolyl-l-cysteinamide
7H-Pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosine-17-acetic acid, 3-(aminocarbonyl)-11-[4-[(aminoiminomethyl)amino]butyl]docosahydro-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxo-
Mpr-Harg-Gly-Asp-Trp-Pro-Cys-NH2,( Disulfide Bridge:1-7)
EFTIFIBATIDE
MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2
MFCD05662245
[11-(4-Carbamimidamidobutyl)-3-carbamoyl-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosin-17-yl]acetic acid
Mpr-Harg-Gly-Asp-Trp-Pro-Cys-NH2,( Disulfide Bridg on Mpr and Cys)
Eptifitide
INTEGRELIN
Eptifibatide Acetate
7H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosine-17-acetic acid, 3-(aminocarbonyl)-11-[4-[(diaminomethylene)amino]butyl]docosahydro-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxo-
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