42867-74-3

42867-74-3 structure
42867-74-3 structure
  • Name: 5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine
  • Chemical Name: [(2S,5R)-5-(2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methyl acetate
  • CAS Number: 42867-74-3
  • Molecular Formula: C11H12N2O5
  • Molecular Weight: 252.22
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2017-01-12 14:14:19
  • Modify Date: 2024-07-14 16:45:34
  • 5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name [(2S,5R)-5-(2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methyl acetate
Synonyms Uridine,2',3'-didehydro-2',3'-dideoxy-,5'-acetate
Description 5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Molecular Formula C11H12N2O5
Molecular Weight 252.22
Exact Mass 252.07500
PSA 90.65000