15379-29-0
15379-29-0 structure
- Name: Uridine, 2',3'-didehydro-2',3'-dideoxy-5-fluoro- (9CI)
- Chemical Name: 5-fluoro-1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidine-2,4-dione
- CAS Number: 15379-29-0
- Molecular Formula: C9H9FN2O4
- Molecular Weight: 228.18
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2017-09-08 17:45:29
- Modify Date: 2024-01-13 11:18:10
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2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 5-fluoro-1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidine-2,4-dione |
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| Synonyms | 2',3'-Didehydro-2',3'-dideoxy-hexopyranosyl cytidine |
| Description | 2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 1.57g/cm3 |
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| Molecular Formula | C9H9FN2O4 |
| Molecular Weight | 228.18 |
| Exact Mass | 228.05500 |
| PSA | 84.32000 |
| Index of Refraction | 1.609 |
|
~75%
15379-29-0 |
| Literature: Joshi, Bhalchandra V.; Rao, T. Sudhakar; Reese, Colin B. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 19 p. 2537 - 2544 |
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~%
15379-29-0 |
| Literature: Coe, Paul L.; Talekar, Ratnakar R.; Walker, Richard T. Journal of Fluorine Chemistry, 1994 , vol. 69, # 1 p. 19 - 24 |
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~%
15379-29-0 |
| Literature: Joshi, Bhalchandra V.; Rao, T. Sudhakar; Reese, Colin B. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 19 p. 2537 - 2544 |
| Precursor 3 | |
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| DownStream 0 | |