5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine

Modify Date: 2024-07-14 16:45:34

5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine Structure
5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine structure
Common Name 5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine
CAS Number 42867-74-3 Molecular Weight 252.22
Density N/A Boiling Point N/A
Molecular Formula C11H12N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine


5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name [(2S,5R)-5-(2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methyl acetate
Synonym More Synonyms

  Biological Activity

Description 5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C11H12N2O5
Molecular Weight 252.22
Exact Mass 252.07500
PSA 90.65000

 Synonyms

Uridine,2',3'-didehydro-2',3'-dideoxy-,5'-acetate