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528-58-5

528-58-5 structure
528-58-5 structure
  • Name: Cyanidin Chloride
  • Chemical Name: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxychromenylium chloride
  • CAS Number: 528-58-5
  • Molecular Formula: C15H11ClO6
  • Molecular Weight: 322.697
  • Catalog: Biochemical Chinese herbal medicine ingredients
  • Create Date: 2018-08-06 06:40:25
  • Modify Date: 2024-01-02 16:15:29
  • Cyanidin Chloride (IdB 1027), a subclass of anthocyanin, displays antioxidant and anti-carcinogenesis properties. Cyanidin Chloride (IdB 1027) inhibits osteoclast formation, hydroxyapatite resorption, and receptor activator of NF-κB ligand (RANKL)-induced osteoclast marker gene expression[1].
Name 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxychromenylium chloride
Synonyms Cyanidolchloride
EINECS 208-438-6
1-Benzopyrylium, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-, chloride (1:1)
3,3‘,4,5,7-Pentahydroxyflavyliumchloride
MFCD00017582
1-Benzopyrylium, 2- (3,4-dihydroxyphenyl)-3,5,7-trihydroxy-, chloride
2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxychromenium chloride
Cyanidin Chloride
Description Cyanidin Chloride (IdB 1027), a subclass of anthocyanin, displays antioxidant and anti-carcinogenesis properties. Cyanidin Chloride (IdB 1027) inhibits osteoclast formation, hydroxyapatite resorption, and receptor activator of NF-κB ligand (RANKL)-induced osteoclast marker gene expression[1].
Related Catalog
In Vitro Cyanidin Chloride (IdB 1027) inhibits receptor activator of NF-κB ligand (RANKL)-induced NF-κB activation, suppresses the degradation of IκB-α and attenuates the phosphorylation of extracellular signal-regulated kinases (ERK). Cyanidin Chloride (IdB 1027) abrogates RANKL-induced calcium oscillations, the activation of nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1), and the expression of c-Fos[1].
In Vivo Cyanidin Chloride (IdB 1027) protects against OVX-induced bone loss in OVX-induced osteoporosis mouse model[1].
References

[1]. Cheng J, et al. Cyanidin Chloride inhibits ovariectomy-induced osteoporosis by suppressing RANKL-mediated osteoclastogenesis and associated signaling pathways. J Cell Physiol. 2018 Mar;233(3):2502-2512.
Molecular Formula C15H11ClO6
Molecular Weight 322.697
Exact Mass 322.024414
PSA 114.29000
Storage condition −20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LK9824000
CHEMICAL NAME :
Flavylium, 3,3'4',5,7-pentahydroxy-, chloride
CAS REGISTRY NUMBER :
528-58-5
LAST UPDATED :
199707
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C15-H11-O6.Cl
MOLECULAR WEIGHT :
322.71

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
>6 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Sex chromosome loss and nondisjunction
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
100 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 246,205,1991
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS LK9824000
HS Code 2932999099
117-39-5 structure

117-39-5

~%

528-58-5 structure

528-58-5
Literature: Malkin; Nierenstein Journal of the American Chemical Society, 1930 , vol. 52, p. 2864,2868 Full Text Show Details Watson; Meek Journal of the Chemical Society, 1915 , vol. 107, p. 1569 Full Text Show Details Watson; Sen Journal of the Chemical Society, 1914 , vol. 105, p. 398 Full Text Show Details Kondo Chem. Zentralbl., 1932 , vol. 103, # II p. 1182
69082-77-5 structure

69082-77-5

~%

528-58-5 structure

528-58-5
Literature: Westhuizen, Jan H. van der; Ferreira, Daneel; Roux, David G. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1220 - 1226
69082-77-5 structure

69082-77-5

~%

528-58-5 structure

528-58-5

2948-76-7 structure

2948-76-7
Literature: Westhuizen, Jan H. van der; Ferreira, Daneel; Roux, David G. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1220 - 1226
65052-93-9 structure

65052-93-9

~%

528-58-5 structure

528-58-5

2948-76-7 structure

2948-76-7
Literature: Westhuizen, Jan H. van der; Ferreira, Daneel; Roux, David G. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1220 - 1226
7647-01-0 structure

7647-01-0
117-39-5 structure

117-39-5

~%

528-58-5 structure

528-58-5
Literature: Malkin; Nierenstein Journal of the American Chemical Society, 1930 , vol. 52, p. 2864,2868 Full Text Show Details Watson; Meek Journal of the Chemical Society, 1915 , vol. 107, p. 1569 Full Text Show Details Watson; Sen Journal of the Chemical Society, 1914 , vol. 105, p. 398 Full Text Show Details Robinson Chemische Berichte, 1934 , vol. 67, p. Abt. A, S. 85 Full Text Show Details Willstaetter; Mallison Justus Liebigs Annalen der Chemie, 1915 , vol. 408, p. 148 Chem. Zentralbl., 1914 , vol. 85, # II p. 1359
858841-91-5 structure

858841-91-5

~%

528-58-5 structure

528-58-5
Literature: Robertson; Robinson Journal of the Chemical Society, 1928 , p. 1526,1530 Full Text Show Details Robinson; Willstaetter Chemische Berichte, 1928 , vol. 61, p. 2506 Full Text Show Details Malkin; Nierenstein Chemische Berichte, 1928 , vol. 61, p. 798 Journal of the American Chemical Society, 1931 , vol. 53, p. 239
51079-25-5 structure

51079-25-5

~%

528-58-5 structure

528-58-5
Literature: Appel; Robinson Journal of the Chemical Society, 1935 , p. 426,428
7647-01-0 structure

7647-01-0
96069-12-4 structure

96069-12-4
64-19-7 structure

64-19-7

~%

528-58-5 structure

528-58-5
Literature: Freudenberg et al. Justus Liebigs Annalen der Chemie, 1935 , vol. 518, p. 37,61
16198-01-9 structure

16198-01-9
56-23-5 structure

56-23-5
128-08-5 structure

128-08-5
94-36-0 structure

94-36-0

~%

Detail
Literature: Ganguli et al. Proceedings - Indian Academy of Sciences, Section A, 1957 , # 46 p. 25,27
HS Code 2907299090
Summary 2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

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title: CAS No. 528-58-5 | Chemsrc address: https://m.chemsrc.com/en/baike/1101659.html

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