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5306-85-4

5306-85-4 structure
5306-85-4 structure
  • Name: 1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol
  • Chemical Name: Isosorbide Dimethyl Ether
  • CAS Number: 5306-85-4
  • Molecular Formula: C8H14O4
  • Molecular Weight: 174.19
  • Catalog: Research Areas Others
  • Create Date: 2018-09-08 12:29:05
  • Modify Date: 2024-01-03 12:04:47
  • Isosorbide dimethyl ether is a biobased high boiling green solvent. Isosorbide dimethyl ether can be used for sustainable ultrafiltration and microfiltration membrane preparation. Isosorbide dimethyl ether can be used as an excipient, such as solvent, penetration aid. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Name Isosorbide Dimethyl Ether
Synonyms D-Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl-
MFCD00064828
EINECS 226-159-8
(3S,3aR,6R,6aR)-3,6-dimethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan
Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl-, D-
Isosorbide DiMethyl Ether
D-Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol
(3R,3aR,6S,6aR)-3,6-Dimethoxyhexahydrofuro[3,2-b]furan
Description Isosorbide dimethyl ether is a biobased high boiling green solvent. Isosorbide dimethyl ether can be used for sustainable ultrafiltration and microfiltration membrane preparation. Isosorbide dimethyl ether can be used as an excipient, such as solvent, penetration aid. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Related Catalog
References

[1]. Russo F, et al. Dimethyl isosorbide as a green solvent for sustainable ultrafiltration and microfiltration membrane preparation[J]. ACS Sustainable Chemistry & Engineering, 2019, 8(1): 659-668.

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.  

Density 1.2±0.1 g/cm3
Boiling Point 236.4±40.0 °C at 760 mmHg
Melting Point -70°C
Molecular Formula C8H14O4
Molecular Weight 174.19
Flash Point 108.3±0.0 °C
Exact Mass 174.089203
PSA 36.92000
LogP -0.65
Vapour Pressure 0.1±0.5 mmHg at 25°C
Index of Refraction 1.466
Safety Phrases S23-S24/25
WGK Germany 3
HS Code 2932999099
HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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