Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,2-Distearoyl-sn-glycero-3-phosphocholine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Top Intermediates Co., Ltd.
China
Product Name: 1,2-Distearoyl-sn-glycero-3-phosphocholine
Price: ￥Inquiry/1kg
Purity: 99.0%
Stocking Period: Inquiry
Contact: Mr. Lin
Email: 302741793@qq.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 1,2-distearoyl-sn-glycero-3-phosphocholine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

816-94-4

816-94-4 structure

Name: 1,2-Distearoyl-sn-glycero-3-phosphocholine
Chemical Name: 1,2-distearoyl-sn-glycero-3-phosphocholine
CAS Number: 816-94-4
Molecular Formula: C₄₄H₈₈NO₈P
Molecular Weight: 790.145
Catalog: Research Areas Others
Create Date: 2018-12-27 17:07:32
Modify Date: 2026-07-01 19:52:31
1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].

Name	1,2-distearoyl-sn-glycero-3-phosphocholine
Synonyms	Dioctadecanoyl-L-α-glycerophosphorylcholine (R)-2,3-Bis(steoyloxy)propyl (2-(triMethylaMMonio)ethyl) phosphate 1,2-Dioleoyl-sn-Glycero-3-Phsophocholine [O-(1-O,2-O-Disteoyl-L-glycero-3-phospho)choline]anion L-β,γ-Disteoyl-α-lecithin 1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine（DSPC） DISTEOYL GLYCEROPHOSPHOCHOLINE 3-sn-phosphatidylcholine, 1,2-disteoyl 1,2-Disteoyl-sn-glycero-3-phosphorylcholine (DSPC), Phosphorylcholine 1,2-Dioctadecanoyl-sn-glycero-3-phophocholine 1,2-Disteoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-disteoyl, L-α-Phosphatidylcholine, disteoyl, L-β,γ-Disteoyl-α-lecithin 18:0 PC (DSPC) DSPC(18:0) Disteoyl sn (2R)-2,3-bis(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate 1,2-disteoyl-sn-glycero-3-phosphocholine DSPC L-1118 L-á-Phosphatidylcholine disteoyl L-α-Phosphatidylcholine, disteoyl L-A-PHOSPHATIDYLCHOLINE DISTEOYL*CRYST SYNTHETIC 18:0 PC 1,2-DSPC EINECS 212-440-2 1,2-DISTEOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE propyl (2-(trimethylammonio) 3-sn-Phosphatidylcholine, 1,2-disteoyl, L-α-Phosphatidylcholine, disteoyl, L-β,γ-Disteoyl-α-lecithin 1,2-Disteoyl-sn-glycero-3-phosphorylcholine (DSPC) Lecithin Impurity 7 L-α-PHOSPHATIDYLCHOLINE, DISTEAROYL Disteoyl-L-ALPHA-phosphatidyl choline Disteoyl-L-a-Lecithin MFCD00036905 3,5,9-Trioxa-4-phosphahtacosan-1-aminium,4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxooctadecyl)oxy]-, inner salt,4-oxide, (7R) (R)-(7-lauroyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphahtacosyl)trimethylammonium 4-oxide DSPC disteoyl phosphatidylcholine Disteoyl-L-α-phosphatidylcholine DISTEOYL LECITHIN L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEOYL 1,2-DIOCTADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Hydrogenated（steic acid）Phosphatidylcholine（DSPC） L-A-PHOSPHATIDYLCHOLINE, DISTEOYL L-α-Phosphatidylcholine disteoyl 1,2-Disteoyl-sn-glycero-3-PC (2R)-2,3-Bis(stearoyloxy)propyl 2-(trimethylammonio)ethyl phosphate L-BETA,GAMMA-DISTEOYL-ALPHA-LECITHIN DSPC reference substance of Disteyl phosphatidylcholine [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate PC(18:0/18:0) 1,2-Disteoyl-sn-glycero-3-phosphocholine> 1,2-Disteoyl-sn-glyeero -3-phosphochoine [(2R)-2,3-disteoyloxypropyl] 2-(trimethylammonio)ethyl phosphate L-b,g-Disteoyl-a-lecithin, DSPC 2,3-Bis(steoyloxy) Ethanaminium, 2-[[[(2R)-2,3-bis[(1-oxooctadecyl)oxy]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt 1,2-DISTEOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE β,γ-Disteoyl-L-α-phosphatidylcholine

Description	1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	In empty lipid nanoparticle (LNP) systems that do not contain siRNA, DSPC-cholesterol resides in outer layers, whereas in loaded systems a portion of the DSPC-cholesterol is internalised together with siRNA[2].
References	[1]. Andrew D Miller. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811. [2]. Jayesh A Kulkarni, et al. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. 2019 Nov 21;11(45):21733-21739.

Melting Point	236 °C
Molecular Formula	C₄₄H₈₈NO₈P
Molecular Weight	790.145
Exact Mass	789.624756
PSA	121.00000
LogP	13.00

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport

Precursor 10
111-63-7 34688-34-1 51063-97-9 6542-05-8
107437-06-9 24529-89-3 66152-20-3 2258-41-5
67-48-1 106654-97-1
DownStream 2
67-48-1 19420-57-6

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