Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Br-C3-methyl ester
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Br-C3-methyl ester
Price: ￥718.0/100g ￥118.0/25g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Br-C3-methyl ester
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Methyl 4-bromobutyrate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

4897-84-1

4897-84-1 structure

4897-84-1 structure

Name: Br-C3-methyl ester
Chemical Name: Methyl 4-Bromobutyrate
CAS Number: 4897-84-1
Molecular Formula: C₅H₉BrO₂
Molecular Weight: 181.028
Catalog: Chemical reagent Organic reagent Ester Methyl ester compound
Create Date: 2018-04-20 08:00:00
Modify Date: 2024-01-03 14:11:42
Br-C3-methyl ester is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1].

Name	Methyl 4-Bromobutyrate
Synonyms	Butanoic acid, 4-bromo-, methyl ester MFCD00041482 Butyric acid, 4-bromo-, methyl ester EINECS 225-523-3 4-Bromobutyric Acid Methyl Ester Methyl 4-bromobutanoate Methyl 4-bromobutyrate

Description	Br-C3-methyl ester is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Binbin Cheng, et al. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.

Density	1.4±0.1 g/cm3
Boiling Point	186.5±0.0 °C at 760 mmHg
Molecular Formula	C₅H₉BrO₂
Molecular Weight	181.028
Flash Point	87.0±13.0 °C
Exact Mass	179.978592
PSA	26.30000
LogP	1.47
Vapour Pressure	0.7±0.3 mmHg at 25°C
Index of Refraction	1.456
Storage condition	Room temperature.
Water Solubility	insoluble

Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S37/39-S26
HS Code	2915900090

Precursor 0
DownStream 9
107903-02-6 111479-52-8 33036-62-3 71-36-3
96-48-0 74-83-9 623-43-8 3724-55-8
88-75-5

HS Code	2915900090
Summary	2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%