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101-21-3

101-21-3 structure
101-21-3 structure
  • Name: Chlorpropham
  • Chemical Name: chlorpropham
  • CAS Number: 101-21-3
  • Molecular Formula: C10H12ClNO2
  • Molecular Weight: 213.661
  • Catalog: Chemical pesticide Plant Growth Regulator
  • Create Date: 2018-02-18 08:00:00
  • Modify Date: 2025-08-23 02:35:47
  • Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules[1][2].
Name chlorpropham
Synonyms Chlorpropham
chlor-IPC
1-methylethyl (3-chlorophenyl)carbamate
MFCD00037108
isopropyl 3-chlorocarbanilate
Carbamic acid, N-(3-chlorophenyl)-, 1-methylethyl ester
propan-2-yl (3-chlorophenyl)carbamate
propan-2-yl N-(3-chlorophenyl)carbamate
EINECS 202-925-7
Isopropyl m-chlorocarbanilate
Bud Nip
Taterpex
Isopropyl (3-chlorophenyl)carbamate
1-methylethyl N-(3-chlorophenyl)carbamate
Description Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules[1][2].
Related Catalog
In Vitro Chlorpropham (1-20 μM; 6 d) inhibits cell division of D. salina cultures[2]. Chlorpropham (10 or 20 μM; 6 d) shows increasement of phytoene in D. salina cultures under red LED light[2].
Density 1.2±0.1 g/cm3
Boiling Point 251.1±23.0 °C at 760 mmHg
Melting Point 41°C
Molecular Formula C10H12ClNO2
Molecular Weight 213.661
Flash Point 105.7±22.6 °C
Exact Mass 213.055649
PSA 38.33000
LogP 3.49
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.561
Water Solubility 0.009 g/100 ml very poor

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FD8050000
CHEMICAL NAME :
Carbanilic acid, m-chloro-, isopropyl ester
CAS REGISTRY NUMBER :
101-21-3
BEILSTEIN REFERENCE NO. :
2211397
LAST UPDATED :
199712
DATA ITEMS CITED :
28
MOLECULAR FORMULA :
C10-H12-Cl-N-O2
MOLECULAR WEIGHT :
213.68
WISWESSER LINE NOTATION :
GR CMVOY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1200 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1092 gm/kg/2Y-C
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
68250 mg/kg/13W-C
TOXIC EFFECTS :
Liver - changes in liver weight Endocrine - changes in spleen weight Blood - methemoglobinemia-carboxyhemoglobin
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3 gm/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
9 gm/kg
SEX/DURATION :
female 6-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Kidney
DOSE/DURATION :
2500 ug/L
REFERENCE :
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,638,1981 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 12,55,1976 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 12,55,1976 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.) V.1-77, 1893-1970. Volume(issue)/page/year: 80,485,1973 TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 63,1,1976 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3 JAN 1993
Symbol GHS07 GHS08 GHS09
GHS07, GHS08, GHS09
Signal Word Warning
Hazard Statements H302-H351-H373-H411
Precautionary Statements P273-P301 + P312 + P330-P391-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;N: Dangerous for the environment;F: Flammable;
Risk Phrases R22
Safety Phrases S61-S36/37-S26
RIDADR UN 3077 9/PG 3
WGK Germany 2
RTECS FD8050000
Packaging Group I; II; III
Hazard Class 6.1
HS Code 2924299035
3296-06-8 structure

3296-06-8

201230-82-2 structure

201230-82-2

67-63-0 structure

67-63-0

~94%

101-21-3 structure

101-21-3

Literature: Ren, Long; Jiao, Ning Chemical Communications, 2014 , vol. 50, # 28 p. 3706 - 3709
590-28-3 structure

590-28-3

108-37-2 structure

108-37-2

67-63-0 structure

67-63-0

~85%

101-21-3 structure

101-21-3

Literature: Yang, Xinye; Zhang, Yihua; Ma, Dawei Advanced Synthesis and Catalysis, 2012 , vol. 354, # 13 p. 2443 - 2446,4
108-42-9 structure

108-42-9

~%

101-21-3 structure

101-21-3

Literature: Chemical Communications, , vol. 50, # 28 p. 3706 - 3709
HS Code 2924299035
Summary 2924299035 2-chlorobenzaldehyde。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%
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